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ZNF676 zinc finger protein 676 [ Homo sapiens (human) ]

Gene ID: 163223, updated on 23-Nov-2021

Summary

Official Symbol
ZNF676provided by HGNC
Official Full Name
zinc finger protein 676provided by HGNC
Primary source
HGNC:HGNC:20429
See related
Ensembl:ENSG00000196109
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 3.0), thyroid (RPKM 2.0) and 14 other tissues See more
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Genomic context

See ZNF676 in Genome Data Viewer
Location:
19p12
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (22179089..22196951, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (22361891..22379753, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene metadherin pseudogene 5 Neighboring gene vomeronasal 1 receptor 85 pseudogene Neighboring gene BCL2 interacting protein 3 pseudogene 30 Neighboring gene uncharacterized LOC105372328

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology.
GeneReviews: Not available
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001411.3NP_001001411.2  zinc finger protein 676

    See identical proteins and their annotated locations for NP_001001411.2

    Status: VALIDATED

    Source sequence(s)
    AC073539, AK097798, BX281304
    Consensus CDS
    CCDS42539.1
    UniProtKB/Swiss-Prot
    Q8N7Q3
    Related
    ENSP00000380310.1, ENST00000397121.3
    Conserved Domains (5) summary
    smart00349
    Location:132
    KRAB; krueppel associated box
    COG5048
    Location:195580
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:507527
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:114135
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:547572
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    22179089..22196951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003315965.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    111923..129785
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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