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ZNF782 zinc finger protein 782 [ Homo sapiens (human) ]

Gene ID: 158431, updated on 5-Jan-2022

Summary

Official Symbol
ZNF782provided by HGNC
Official Full Name
zinc finger protein 782provided by HGNC
Primary source
HGNC:HGNC:33110
See related
Ensembl:ENSG00000196597
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in testis (RPKM 1.8), thyroid (RPKM 1.0) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF782 in Genome Data Viewer
Location:
9q22.33
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (96815628..96876698, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (99578551..99616796, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene makorin ring finger protein 1 pseudogene Neighboring gene zinc finger protein 510 Neighboring gene Sharpr-MPRA regulatory region 3853 Neighboring gene cyclin Y like 1 pseudogene Neighboring gene proline-rich nuclear receptor coactivator 2-like Neighboring gene prothymosin alpha pseudogene 11

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ16636

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001662.3NP_001001662.1  zinc finger protein 782 isoform a

    See identical proteins and their annotated locations for NP_001001662.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AK131468, AL158827, AL540705
    Consensus CDS
    CCDS35075.1
    UniProtKB/Swiss-Prot
    Q6ZMW2
    Related
    ENSP00000419397.1, ENST00000481138.6
    Conserved Domains (5) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:392697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:660685
    zf-H2C2_2; Zinc-finger double domain
  2. NM_001346991.2NP_001333920.1  zinc finger protein 782 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL158827
    Consensus CDS
    CCDS35075.1
    UniProtKB/Swiss-Prot
    Q6ZMW2
  3. NM_001346993.2NP_001333922.1  zinc finger protein 782 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AL158827
  4. NM_001346995.2NP_001333924.1  zinc finger protein 782 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate exons compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AL158827
    Conserved Domains (3) summary
    COG5048
    Location:300555
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:276300
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    96815628..96876698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011518315.2XP_011516617.1  zinc finger protein 782 isoform X1

    See identical proteins and their annotated locations for XP_011516617.1

    UniProtKB/Swiss-Prot
    Q6ZMW2
    Conserved Domains (5) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:392697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:660685
    zf-H2C2_2; Zinc-finger double domain
  2. XM_011518320.2XP_011516622.1  zinc finger protein 782 isoform X2

    See identical proteins and their annotated locations for XP_011516622.1

    Conserved Domains (5) summary
    smart00349
    Location:361
    KRAB; krueppel associated box
    COG5048
    Location:386691
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:586606
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:341
    KRAB; KRAB box
    pfam13465
    Location:654679
    zf-H2C2_2; Zinc-finger double domain
  3. XM_011518318.3XP_011516620.1  zinc finger protein 782 isoform X1

    See identical proteins and their annotated locations for XP_011516620.1

    UniProtKB/Swiss-Prot
    Q6ZMW2
    Conserved Domains (5) summary
    smart00349
    Location:867
    KRAB; krueppel associated box
    COG5048
    Location:392697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:847
    KRAB; KRAB box
    pfam13465
    Location:660685
    zf-H2C2_2; Zinc-finger double domain
  4. XM_024447430.1XP_024303198.1  zinc finger protein 782 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:300555
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:276300
    zf-H2C2_2; Zinc-finger double domain
  5. XM_017014343.2XP_016869832.1  zinc finger protein 782 isoform X2

    Conserved Domains (5) summary
    smart00349
    Location:361
    KRAB; krueppel associated box
    COG5048
    Location:386691
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:586606
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:341
    KRAB; KRAB box
    pfam13465
    Location:654679
    zf-H2C2_2; Zinc-finger double domain
  6. XM_024447431.1XP_024303199.1  zinc finger protein 782 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:300555
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:276300
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_001746208.2 RNA Sequence

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