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ZNF782 zinc finger protein 782 [ Homo sapiens (human) ]

Gene ID: 158431, updated on 12-Apr-2026
Official Symbol
ZNF782provided by HGNC
Official Full Name
zinc finger protein 782provided by HGNC
Primary source
HGNC:HGNC:33110
See related
Ensembl:ENSG00000196597 AllianceGenome:HGNC:33110
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in testis (RPKM 1.8), thyroid (RPKM 1.0) and 25 other tissues See more
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ZNF782 in Genome Data Viewer
Location:
9q22.33
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (96816164..96933806, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (108957160..109105571, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (99578551..99616796, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene makorin ring finger protein 10, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20091 Neighboring gene zinc finger protein 510 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20092 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20093 Neighboring gene Sharpr-MPRA regulatory region 3853 Neighboring gene cyclin Y like 1 pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28655 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr9:99636216-99637415 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr9:99646252-99647451 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:99680095-99680594 Neighboring gene NANOG hESC enhancer GRCh37_chr9:99680882-99681400 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:99686833-99687376 Neighboring gene prothymosin alpha pseudogene 11 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:99693219-99694104 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:99694105-99694990 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:99697969-99698597 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:99698598-99699226 Neighboring gene PNRC2 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:99701353-99701853 Neighboring gene NUT family member 2G Neighboring gene solute carrier family 71 member 3, pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr9:99739460-99739668 Neighboring gene yrdC N(6)-threonylcarbamoyltransferase domain containing pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:99750992-99751492 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20094 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20095 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20096 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20097 Neighboring gene cathepsin V

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci. Lei SF, et al. Hum Genet, 2009 Feb. PMID 19030899, Free PMC Article
  2. Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. Moutaoufik MT, et al. iScience, 2019 Sep 27. PMID 31536960, Free PMC Article
  3. DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples. Jiao F, et al. J Proteome Res, 2024 Aug 2. PMID 38334954, Free PMC Article
  4. The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis. Capalbo L, et al. Nat Commun, 2019 Oct 4. PMID 31586073, Free PMC Article
  5. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The present results suggest that the genomic region containing the ZNP510 and ZNP782 genes is an ethnic specific locus associated with stature variation in Chinese.
    Title: Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.
  2. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
    Title: Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.
Submit: New GeneRIF Correction

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ16636

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
zinc finger protein 782

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001662.3 → NP_001001662.1  zinc finger protein 782 isoform a

    See identical proteins and their annotated locations for NP_001001662.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AK131468, AL158827, AL540705
    Consensus CDS
    CCDS35075.1
    UniProtKB/Swiss-Prot
    B2RNR0, Q6ZMW2
    Related
    ENSP00000419397.1, ENST00000481138.6
    Conserved Domains (5) summary
    smart00349
    Location:8 → 67
    KRAB; krueppel associated box
    COG5048
    Location:392 → 697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592 → 612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:8 → 47
    KRAB; KRAB box
    pfam13465
    Location:660 → 685
    zf-H2C2_2; Zinc-finger double domain

  2. NM_001346991.2 → NP_001333920.1  zinc finger protein 782 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AL158827
    Consensus CDS
    CCDS35075.1
    UniProtKB/Swiss-Prot
    B2RNR0, Q6ZMW2
    Related
    ENSP00000563278.1, ENST00000893219.1

  3. NM_001346993.2 → NP_001333922.1  zinc finger protein 782 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two alternate exons compared to variant 1. The resulting isoform (b) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AL158827

  4. NM_001346995.2 → NP_001333924.1  zinc finger protein 782 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks two alternate exons compared to variant 1. The resulting isoform (c) is shorter at the N-terminus compared to isoform a.
    Source sequence(s)
    AL158827
    Conserved Domains (3) summary
    COG5048
    Location:300 → 555
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460 → 480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:276 → 300
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    96816164..96933806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422874.1 → XP_047278830.1  zinc finger protein 782 isoform X3

  2. XM_011518315.3 → XP_011516617.1  zinc finger protein 782 isoform X1

    See identical proteins and their annotated locations for XP_011516617.1

    UniProtKB/Swiss-Prot
    B2RNR0, Q6ZMW2
    Related
    ENSP00000440624.2, ENST00000535338.5
    Conserved Domains (5) summary
    smart00349
    Location:8 → 67
    KRAB; krueppel associated box
    COG5048
    Location:392 → 697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592 → 612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:8 → 47
    KRAB; KRAB box
    pfam13465
    Location:660 → 685
    zf-H2C2_2; Zinc-finger double domain

  3. XM_047422870.1 → XP_047278826.1  zinc finger protein 782 isoform X1

    UniProtKB/Swiss-Prot
    B2RNR0, Q6ZMW2

  4. XM_011518320.3 → XP_011516622.1  zinc finger protein 782 isoform X2

    See identical proteins and their annotated locations for XP_011516622.1

    Related
    ENSP00000563277.1, ENST00000893218.1
    Conserved Domains (5) summary
    smart00349
    Location:3 → 61
    KRAB; krueppel associated box
    COG5048
    Location:386 → 691
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:586 → 606
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 41
    KRAB; KRAB box
    pfam13465
    Location:654 → 679
    zf-H2C2_2; Zinc-finger double domain

  5. XM_047422872.1 → XP_047278828.1  zinc finger protein 782 isoform X2

  6. XM_011518318.4 → XP_011516620.1  zinc finger protein 782 isoform X1

    See identical proteins and their annotated locations for XP_011516620.1

    UniProtKB/Swiss-Prot
    B2RNR0, Q6ZMW2
    Related
    ENSP00000587576.1, ENST00000917517.1
    Conserved Domains (5) summary
    smart00349
    Location:8 → 67
    KRAB; krueppel associated box
    COG5048
    Location:392 → 697
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:592 → 612
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:8 → 47
    KRAB; KRAB box
    pfam13465
    Location:660 → 685
    zf-H2C2_2; Zinc-finger double domain

  7. XM_047422871.1 → XP_047278827.1  zinc finger protein 782 isoform X2

    Related
    ENSP00000563276.1, ENST00000893217.1

  8. XM_017014343.3 → XP_016869832.1  zinc finger protein 782 isoform X2

    Conserved Domains (5) summary
    smart00349
    Location:3 → 61
    KRAB; krueppel associated box
    COG5048
    Location:386 → 691
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:586 → 606
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:3 → 41
    KRAB; KRAB box
    pfam13465
    Location:654 → 679
    zf-H2C2_2; Zinc-finger double domain

  9. XM_047422873.1 → XP_047278829.1  zinc finger protein 782 isoform X3

  10. XM_024447431.2 → XP_024303199.1  zinc finger protein 782 isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:300 → 555
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:460 → 480
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:276 → 300
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. XR_007061256.1 RNA Sequence

  2. XR_007061255.1 RNA Sequence

  3. XR_007061254.1 RNA Sequence

  4. XR_007061253.1 RNA Sequence

  5. XR_001746208.3 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    108957160..109105571 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054362170.1 → XP_054218145.1  zinc finger protein 782 isoform X3

  2. XM_054362164.1 → XP_054218139.1  zinc finger protein 782 isoform X1

  3. XM_054362163.1 → XP_054218138.1  zinc finger protein 782 isoform X1

  4. XM_054362162.1 → XP_054218137.1  zinc finger protein 782 isoform X1

  5. XM_054362168.1 → XP_054218143.1  zinc finger protein 782 isoform X3

  6. XM_054362167.1 → XP_054218142.1  zinc finger protein 782 isoform X2

  7. XM_054362166.1 → XP_054218141.1  zinc finger protein 782 isoform X2

  8. XM_054362161.1 → XP_054218136.1  zinc finger protein 782 isoform X1

  9. XM_054362165.1 → XP_054218140.1  zinc finger protein 782 isoform X2

  10. XM_054362169.1 → XP_054218144.1  zinc finger protein 782 isoform X3

RNA

  1. XR_008487953.1 RNA Sequence

  2. XR_008487952.1 RNA Sequence

  3. XR_008487951.1 RNA Sequence

  4. XR_008487950.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZMW2.1 GenPept UniProtKB/Swiss-Prot:Q6ZMW2

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