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ZNF738 zinc finger protein 738 [ Homo sapiens (human) ]

Gene ID: 148203, updated on 26-Oct-2022

Summary

Official Symbol
ZNF738provided by HGNC
Official Full Name
zinc finger protein 738provided by HGNC
Primary source
HGNC:HGNC:32469
See related
Ensembl:ENSG00000172687 AllianceGenome:HGNC:32469
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary (RPKM 1.4), lymph node (RPKM 1.2) and 23 other tissues See more
Orthologs
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Genomic context

See ZNF738 in Genome Data Viewer
Location:
19p12
Exon count:
7
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (21359000..21388582)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (21497531..21527122)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (21541802..21571384)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase assembly protein COX16 homolog, mitochondrial-like Neighboring gene vomeronasal 1 receptor 83 pseudogene Neighboring gene zinc finger protein 708 Neighboring gene BCL2 interacting protein 3 pseudogene 25 Neighboring gene iron-sulfur cluster assembly 1 homolog (S. cerevisiae) pseudogene Neighboring gene zinc finger protein 493 Neighboring gene uncharacterized LOC105372321

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in protein polyubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger protein 738
Names
protein ZNF738

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355237.2NP_001342166.1  zinc finger protein 738 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC010615, AC022432
    Consensus CDS
    CCDS92573.1
    UniProtKB/Swiss-Prot
    A8K4N7
    UniProtKB/TrEMBL
    A0A804HJ59
    Related
    ENSP00000507366.1, ENST00000683779.1
    Conserved Domains (3) summary
    smart00349
    Location:3595
    KRAB; krueppel associated box
    COG5048
    Location:149374
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:290310
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001355239.2NP_001342168.1  zinc finger protein 738 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC010615, AC022432
    Consensus CDS
    CCDS86732.1
    Related
    ENSP00000311957.3, ENST00000311015.7
    Conserved Domains (1) summary
    smart00349
    Location:3595
    KRAB; krueppel associated box
  3. NM_001355240.2NP_001342169.1  zinc finger protein 738 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC010615, AC022432
    Consensus CDS
    CCDS86733.1
    UniProtKB/TrEMBL
    E9PE46
    Related
    ENSP00000370252.4, ENST00000380870.8
    Conserved Domains (1) summary
    smart00349
    Location:3595
    KRAB; krueppel associated box
  4. NM_001355241.2NP_001342170.1  zinc finger protein 738 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC010615, AC022432
    Related
    ENSP00000471336.1, ENST00000597810.5
    Conserved Domains (1) summary
    smart00349
    Location:3595
    KRAB; krueppel associated box

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    21359000..21388582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438272.1XP_047294228.1  zinc finger protein 738 isoform X1

  2. XM_047438273.1XP_047294229.1  zinc finger protein 738 isoform X2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    21497531..21527122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)