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ZNF565 zinc finger protein 565 [ Homo sapiens (human) ]

Gene ID: 147929, updated on 24-Nov-2020

Summary

Official Symbol
ZNF565provided by HGNC
Official Full Name
zinc finger protein 565provided by HGNC
Primary source
HGNC:HGNC:26726
See related
Ensembl:ENSG00000196357 MIM:614275
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in testis (RPKM 2.4), brain (RPKM 1.4) and 25 other tissues See more
Orthologs

Genomic context

See ZNF565 in Genome Data Viewer
Location:
19q13.12
Exon count:
10
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (36182060..36245928, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (36673187..36705986, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene calpain small subunit 1 Neighboring gene cytochrome c oxidase subunit 7A1 Neighboring gene uncharacterized LOC107985304 Neighboring gene zinc finger protein 146 Neighboring gene uncharacterized LOC100134317 Neighboring gene long intergenic non-protein coding RNA 665

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36991

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042474.2NP_001035939.1  zinc finger protein 565 isoform 1

    See identical proteins and their annotated locations for NP_001035939.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1. Variants 1-4 encode the same isoform (1).
    Source sequence(s)
    AC008848, DA766324
    Consensus CDS
    CCDS12491.1
    UniProtKB/Swiss-Prot
    Q8N9K5
    Related
    ENSP00000376013.1, ENST00000392173.6
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. NM_001366188.1NP_001353117.1  zinc finger protein 565 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same isoform (1).
    Source sequence(s)
    AC008848, AC012617
    Related
    ENSP00000347234.5, ENST00000355114.9
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. NM_001366189.1NP_001353118.1  zinc finger protein 565 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same isoform (1).
    Source sequence(s)
    AC008848, AC012617
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. NM_001366190.1NP_001353119.1  zinc finger protein 565 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and lacks a portion of the 5' coding region compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AC008848, AC012617
    Conserved Domains (2) summary
    COG5048
    Location:103433
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. NM_152477.5NP_689690.3  zinc finger protein 565 isoform 1

    See identical proteins and their annotated locations for NP_689690.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same isoform (1).
    Source sequence(s)
    AC008848, CB960081, DA473136
    Consensus CDS
    CCDS12491.1
    UniProtKB/Swiss-Prot
    Q8N9K5
    Related
    ENSP00000306869.5, ENST00000304116.10
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    36182060..36245928 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017026343.1XP_016881832.1  zinc finger protein 565 isoform X2

    Conserved Domains (2) summary
    COG5048
    Location:103433
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:244264
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011526512.2XP_011524814.1  zinc finger protein 565 isoform X1

    See identical proteins and their annotated locations for XP_011524814.1

    UniProtKB/Swiss-Prot
    Q8N9K5
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_011526514.2XP_011524816.1  zinc finger protein 565 isoform X1

    See identical proteins and their annotated locations for XP_011524816.1

    UniProtKB/Swiss-Prot
    Q8N9K5
    Conserved Domains (3) summary
    smart00349
    Location:666
    KRAB; krueppel associated box
    COG5048
    Location:193498
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:309329
    ZF_C2H2; C2H2 Zn finger [structural motif]
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