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Dlg1 discs large MAGUK scaffold protein 1 [ Mus musculus (house mouse) ]

Gene ID: 13383, updated on 8-Jan-2023

Summary

Official Symbol
Dlg1provided by MGI
Official Full Name
discs large MAGUK scaffold protein 1provided by MGI
Primary source
MGI:MGI:107231
See related
Ensembl:ENSMUSG00000022770 AllianceGenome:MGI:107231
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Dlgh1; SAP97; SAP-97; mKIAA4187; E-dlg/SAP97; B130052P05Rik
Summary
Enables molecular adaptor activity and potassium channel regulator activity. A structural constituent of postsynaptic density. Involved in several processes, including neurotransmitter receptor localization to postsynaptic specialization membrane; regulation of potassium ion transmembrane transport; and regulation of ventricular cardiac muscle cell action potential. Acts upstream of or within several processes, including animal organ development; hard palate development; and negative regulation of cell population proliferation. Located in several cellular components, including basolateral plasma membrane; immunological synapse; and lateral loop. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and surface ectoderm. Human ortholog(s) of this gene implicated in invasive ductal carcinoma. Orthologous to human DLG1 (discs large MAGUK scaffold protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cortex adult (RPKM 13.3), bladder adult (RPKM 13.0) and 28 other tissues See more
Orthologs
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Try the new Transcript table

Genomic context

See Dlg1 in Genome Data Viewer
Location:
16 B2; 16 22.4 cM
Exon count:
31
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (31482261..31692174)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (31663443..31873356)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene predicted gene 536 Neighboring gene predicted gene, 24879 Neighboring gene nucleoporin 37 pseudogene Neighboring gene melanotransferrin Neighboring gene predicted gene, 52243 Neighboring gene predicted gene, 34476

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA4187

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L27 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables PDZ domain binding ISO
Inferred from Sequence Orthology
more info
 
enables ionotropic glutamate receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables kinase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
enables kinesin binding ISO
Inferred from Sequence Orthology
more info
 
enables mitogen-activated protein kinase kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular adaptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phosphatase binding ISO
Inferred from Sequence Orthology
more info
 
enables potassium channel regulator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables potassium channel regulator activity ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
enables structural constituent of postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
enables structural constituent of postsynaptic density IEP
Inferred from Expression Pattern
more info
PubMed 
enables structural constituent of postsynaptic density IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transmembrane transporter binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within T cell activation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within T cell cytokine production IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in actin filament organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within activation of protein kinase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within amyloid precursor protein metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in astral microtubule organization ISO
Inferred from Sequence Orthology
more info
 
involved_in bicellular tight junction assembly ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within branching involved in ureteric bud morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell-cell adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to brain-derived neurotrophic factor stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cortical actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in cortical microtubule organization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within embryonic skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in endothelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in establishment of centrosome localization ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within hard palate development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within immunological synapse formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within lens development in camera-type eye IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within membrane raft organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of G1/S transition of mitotic cell cycle ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within negative regulation of epithelial cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of p38MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within negative regulation of protein kinase B signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IDA
Inferred from Direct Assay
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in neurotransmitter receptor localization to postsynaptic specialization membrane ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within peristalsis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within positive regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in positive regulation of developmental growth TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of multicellular organism growth TAS
Traceable Author Statement
more info
PubMed 
involved_in positive regulation of potassium ion transport ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of protein kinase B signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within protein localization IGI
Inferred from Genetic Interaction
more info
PubMed 
acts_upstream_of_or_within protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization to plasma membrane ISO
Inferred from Sequence Orthology
more info
 
involved_in protein-containing complex localization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of cell shape ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of membrane potential IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of membrane potential ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of myelination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of potassium ion export across plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of potassium ion import IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of protein localization ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein localization to synapse IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of protein localization to synapse ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of ventricular cardiac muscle cell action potential IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within reproductive structure development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within smooth muscle tissue development IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within tissue morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within ureteric bud development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
part_of MPP7-DLG1-LIN7 complex ISO
Inferred from Sequence Orthology
more info
 
located_in T-tubule ISO
Inferred from Sequence Orthology
more info
 
located_in adherens junction TAS
Traceable Author Statement
more info
PubMed 
located_in basal plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in basement membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in basolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in basolateral plasma membrane TAS
Traceable Author Statement
more info
PubMed 
located_in bicellular tight junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cell-cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse IEP
Inferred from Expression Pattern
more info
PubMed 
is_active_in glutamatergic synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in immunological synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in immunological synapse ISO
Inferred from Sequence Orthology
more info
 
located_in lateral loop IDA
Inferred from Direct Assay
more info
PubMed 
located_in lateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in lateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule ISO
Inferred from Sequence Orthology
more info
 
located_in microvillus ISO
Inferred from Sequence Orthology
more info
 
located_in myelin sheath abaxonal region IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuromuscular junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuromuscular junction IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in neuron projection ISO
Inferred from Sequence Orthology
more info
 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in node of Ranvier IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in paranode region of axon ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
located_in postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
is_active_in postsynaptic density membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in postsynaptic density, intracellular component ISO
Inferred from Sequence Orthology
more info
 
located_in presynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synapse IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in synaptic membrane ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
disks large homolog 1
Names
discs, large homolog 1
embryo-dlg/synapse-associated protein 97

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252433.1NP_001239362.1  disks large homolog 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon and uses an alternate splice site in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC129214, AY159380, BU058018
    UniProtKB/Swiss-Prot
    Q811D0
    Conserved Domains (8) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00072
    Location:713880
    GuKc; Guanylate kinase homologues
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:702880
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:462
    L27_1; L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. NM_001252434.1NP_001239363.1  disks large homolog 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two exons and includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
    Source sequence(s)
    AC129214, AK143780, AY159380, BU058018
    Consensus CDS
    CCDS57026.1
    UniProtKB/Swiss-Prot
    Q811D0
    UniProtKB/TrEMBL
    H7BWY4, Q3UP61
    Related
    ENSMUSP00000023454.6, ENSMUST00000023454.12
    Conserved Domains (8) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00072
    Location:692859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:681859
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:462
    L27_1; L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. NM_001252435.1NP_001239364.1  disks large homolog 1 isoform 4

    See identical proteins and their annotated locations for NP_001239364.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, lacks an exon and includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
    Source sequence(s)
    AC126055, AC129214
    Consensus CDS
    CCDS57025.1
    UniProtKB/Swiss-Prot
    Q811D0, Q8CGN7
    Related
    ENSMUSP00000110859.2, ENSMUST00000115205.9
    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:714892
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. NM_001252436.1NP_001239365.1  disks large homolog 1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR and has multiple differences in the coding region, including the use of an alternate start codon, compared to variant 1. The encoded isoform (5) is shorter and has a distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AC129214, AK142893, CF164686
    Consensus CDS
    CCDS57027.1
    UniProtKB/TrEMBL
    A0A8C6GA65, D3Z3B8
    Related
    ENSMUSP00000110850.2, ENSMUST00000115196.8
    Conserved Domains (7) summary
    cd12031
    Location:499565
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00072
    Location:654821
    GuKc; Guanylate kinase homologues
    smart00228
    Location:380464
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:643821
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:321382
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:107140
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. NM_001357281.1NP_001344210.1  disks large homolog 1 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC126055, AC129214
    Conserved Domains (6) summary
    cd12031
    Location:453519
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:334418
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:95179
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:592770
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:275336
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:1094
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  6. NM_001357282.1NP_001344211.1  disks large homolog 1 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC126055, AC129214
    Conserved Domains (7) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:688866
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:462
    L27_1; L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  7. NM_007862.3NP_031888.2  disks large homolog 1 isoform 1

    See identical proteins and their annotated locations for NP_031888.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC129214, BC057118, BU058018
    Consensus CDS
    CCDS28107.1
    UniProtKB/Swiss-Prot
    Q811D0
    UniProtKB/TrEMBL
    A0A8C6GAR3
    Related
    ENSMUSP00000064280.8, ENSMUST00000064477.14
    Conserved Domains (8) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00072
    Location:747914
    GuKc; Guanylate kinase homologues
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:736914
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:462
    L27_1; L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

RNA

  1. NR_045516.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks two exons, includes an alternate exon, and uses an alternate internal splice site, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC129214, AK220189, BU058018
    Related
    ENSMUST00000132176.8

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    31482261..31692174
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521761.4XP_006521824.1  disks large homolog 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C6GAD8
    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:748926
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  2. XM_006521763.4XP_006521826.1  disks large homolog 1 isoform X3

    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:743921
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  3. XM_006521762.4XP_006521825.1  disks large homolog 1 isoform X2

    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:747925
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  4. XM_017316865.2XP_017172354.1  disks large homolog 1 isoform X4

    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:735913
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  5. XM_006521765.4XP_006521828.1  disks large homolog 1 isoform X6

    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:726904
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  6. XM_006521766.4XP_006521829.1  disks large homolog 1 isoform X8

    UniProtKB/TrEMBL
    E9Q9H0
    Related
    ENSMUSP00000110855.2, ENSMUST00000115201.8
    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:721899
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  7. XM_006521768.4XP_006521831.1  disks large homolog 1 isoform X10

    See identical proteins and their annotated locations for XP_006521831.1

    UniProtKB/Swiss-Prot
    Q811D0, Q8CGN7
    Related
    ENSMUSP00000097581.4, ENSMUST00000100001.10
    Conserved Domains (7) summary
    cd12031
    Location:582648
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:463547
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:714892
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:404465
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  8. XM_006521764.5XP_006521827.1  disks large homolog 1 isoform X5

    Conserved Domains (7) summary
    cd12031
    Location:567633
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:448532
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:733911
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:406450
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  9. XM_036159767.1XP_036015660.1  disks large homolog 1 isoform X7

    Conserved Domains (7) summary
    cd12031
    Location:567633
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:448532
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:224308
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:721899
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:406450
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106223
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  10. XM_006521767.5XP_006521830.1  disks large homolog 1 isoform X9

    UniProtKB/TrEMBL
    A0A8C6G9T8
    Conserved Domains (7) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:715893
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  11. XM_030248959.2XP_030104819.1  disks large homolog 1 isoform X11

    Conserved Domains (7) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:703881
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  12. XM_030248960.2XP_030104820.1  disks large homolog 1 isoform X12

    Conserved Domains (7) summary
    cd12031
    Location:549615
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:430514
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:693871
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:371432
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  13. XM_017316872.1XP_017172361.1  disks large homolog 1 isoform X25

    Conserved Domains (7) summary
    cd12031
    Location:534600
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:415499
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:191275
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:700878
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:262
    L27_1
    pfam10600
    Location:373417
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:106190
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  14. XM_006521770.5XP_006521833.1  disks large homolog 1 isoform X14

    Conserved Domains (6) summary
    cd12031
    Location:486552
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:367451
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:128212
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:652830
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:308369
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:10127
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  15. XM_030248962.2XP_030104822.1  disks large homolog 1 isoform X18

    Conserved Domains (6) summary
    cd12031
    Location:453519
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:334418
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:95179
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:619797
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:275336
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:1094
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  16. XM_017316869.2XP_017172358.1  disks large homolog 1 isoform X22

    Conserved Domains (6) summary
    cd12031
    Location:453519
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:334418
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:95179
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:597775
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:275336
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:1094
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  17. XM_006521769.4XP_006521832.1  disks large homolog 1 isoform X13

    Conserved Domains (7) summary
    cd12031
    Location:499565
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:380464
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    COG3087
    Location:30130
    FtsN; Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning]
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:665843
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:321382
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:107140
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  18. XM_030248961.2XP_030104821.1  disks large homolog 1 isoform X16

    Conserved Domains (7) summary
    cd12031
    Location:499565
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:380464
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    COG3087
    Location:30130
    FtsN; Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning]
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:631809
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:321382
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:107140
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  19. XM_017316867.3XP_017172356.1  disks large homolog 1 isoform X17

    Conserved Domains (7) summary
    cd12031
    Location:484550
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:365449
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    COG3087
    Location:30130
    FtsN; Cell division protein FtsN [Cell cycle control, cell division, chromosome partitioning]
    cd00992
    Location:141225
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:628806
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:323367
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:107140
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  20. XM_006521771.4XP_006521834.1  disks large homolog 1 isoform X15

    Conserved Domains (6) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:347431
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:632810
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:78107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  21. XM_006521772.4XP_006521835.1  disks large homolog 1 isoform X19

    UniProtKB/TrEMBL
    A0A8C6GAT9
    Conserved Domains (6) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:347431
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:610788
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:78107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  22. XM_036159768.1XP_036015661.1  disks large homolog 1 isoform X20

    Conserved Domains (6) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:347431
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:605783
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:29107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  23. XM_006521773.4XP_006521836.1  disks large homolog 1 isoform X21

    Conserved Domains (6) summary
    cd12031
    Location:466532
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:347431
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:598776
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:288349
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:78107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  24. XM_036159769.1XP_036015662.1  disks large homolog 1 isoform X23

    Conserved Domains (6) summary
    cd12031
    Location:451517
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:332416
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:595773
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:290334
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:29107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
  25. XM_036159770.1XP_036015663.1  disks large homolog 1 isoform X24

    Conserved Domains (6) summary
    cd12031
    Location:451517
    SH3_DLG1; Src Homology 3 domain of Disks Large homolog 1
    smart00228
    Location:332416
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:108192
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:590768
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:290334
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:29107
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

RNA

  1. XR_004939156.1 RNA Sequence

  2. XR_004939157.1 RNA Sequence

  3. XR_004939159.1 RNA Sequence

  4. XR_004939158.1 RNA Sequence