Format

Send to:

Choose Destination

ZSWIM7 zinc finger SWIM-type containing 7 [ Homo sapiens (human) ]

Gene ID: 125150, updated on 9-Feb-2020

Summary

Official Symbol
ZSWIM7provided by HGNC
Official Full Name
zinc finger SWIM-type containing 7provided by HGNC
Primary source
HGNC:HGNC:26993
See related
Ensembl:ENSG00000214941 MIM:614535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SWS1
Expression
Ubiquitous expression in kidney (RPKM 6.2), adrenal (RPKM 6.1) and 25 other tissues See more
Orthologs

Genomic context

See ZSWIM7 in Genome Data Viewer
Location:
17p12
Exon count:
6
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (15976560..15999704, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15879874..15903006, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371557 Neighboring gene LCR17pA recombination region Neighboring gene adenosine A2b receptor Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene nuclear receptor corepressor 1 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 11 Neighboring gene ribosomal protein L22 pseudogene 21

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Gene-Smoking Interactions Identify Several Novel Blood Pressure Loci in the Framingham Heart Study.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein stabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
Shu complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Shu complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
zinc finger SWIM domain-containing protein 7
Names
SWIM domain-containing and Srs2-interacting protein 1 homolog
SWIM-type zinc finger domain-containing protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042697.2NP_001036162.1  zinc finger SWIM domain-containing protein 7

    See identical proteins and their annotated locations for NP_001036162.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC006251, BU075283, DQ530600
    Consensus CDS
    CCDS42266.1
    UniProtKB/Swiss-Prot
    Q19AV6
    UniProtKB/TrEMBL
    A0A024RD64
    Related
    ENSP00000382218.1, ENST00000399277.6
    Conserved Domains (1) summary
    pfam04434
    Location:83112
    SWIM; SWIM zinc finger
  2. NM_001042698.2NP_001036163.1  zinc finger SWIM domain-containing protein 7

    See identical proteins and their annotated locations for NP_001036163.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC006251, BU075283, DQ530600
    Consensus CDS
    CCDS42266.1
    UniProtKB/Swiss-Prot
    Q19AV6
    UniProtKB/TrEMBL
    A0A024RD64
    Related
    ENSP00000419138.1, ENST00000472495.5
    Conserved Domains (1) summary
    pfam04434
    Location:83112
    SWIM; SWIM zinc finger

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    15976560..15999704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center