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RSKR ribosomal protein S6 kinase related [ Homo sapiens (human) ]

Gene ID: 124923, updated on 13-Mar-2020

Summary

Official Symbol
RSKRprovided by HGNC
Official Full Name
ribosomal protein S6 kinase relatedprovided by HGNC
Primary source
HGNC:HGNC:26314
See related
Ensembl:ENSG00000167524
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGK494
Expression
Broad expression in testis (RPKM 3.9), brain (RPKM 1.9) and 23 other tissues See more
Orthologs

Genomic context

See RSKR in Genome Data Viewer
Location:
17q11.2
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (28607963..28614185, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (26934799..26941377, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene aldolase, fructose-bisphosphate C Neighboring gene sperm associated antigen 5 Neighboring gene SPAG5 antisense RNA 1 Neighboring gene KIAA0100 Neighboring gene stromal cell derived factor 2 Neighboring gene ribosomal protein S12 pseudogene 28

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: SPAG5

Homology

Clone Names

  • FLJ25006, FLJ78978, MGC39533

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ribosomal protein S6 kinase-related protein
Names
sugen kinase 494
NP_001167574.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001174103.2NP_001167574.1  ribosomal protein S6 kinase-related protein

    Status: VALIDATED

    Source sequence(s)
    AC005726
    UniProtKB/TrEMBL
    L7N484
    Related
    ENSP00000301037.4, ENST00000301037.10
    Conserved Domains (2) summary
    smart00220
    Location:108324
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05123
    Location:115359
    STKc_AGC; Catalytic domain of AGC family Serine/Threonine Kinases

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    28607963..28614185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_144610.1: Suppressed sequence

    Description
    NM_144610.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
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