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Ccnf cyclin F [ Mus musculus (house mouse) ]

Gene ID: 12449, updated on 23-Jun-2021

Summary

Official Symbol
Ccnfprovided by MGI
Official Full Name
cyclin Fprovided by MGI
Primary source
MGI:MGI:102551
See related
Ensembl:ENSMUSG00000072082
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CycF; Fbxo; Fbxo1
Expression
Broad expression in liver E14.5 (RPKM 29.9), thymus adult (RPKM 27.8) and 18 other tissues See more
Orthologs
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Genomic context

See Ccnf in Genome Data Viewer
Location:
17 A3.3; 17 12.32 cM
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (24442204..24470383, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (24223230..24251409, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (24360177..24388354, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 24 Neighboring gene netrin 3 Neighboring gene tubulin epsilon and delta complex 2 Neighboring gene microRNA 5134 Neighboring gene microRNA 6965 Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 17 Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 3 Neighboring gene predicted gene, 25618

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 
located_in cell junction ISO
Inferred from Sequence Orthology
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
cyclin-F
Names
G2/mitotic-specific cyclin-F

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007634.4NP_031660.3  cyclin-F

    See identical proteins and their annotated locations for NP_031660.3

    Status: PROVISIONAL

    Source sequence(s)
    AK159594
    Consensus CDS
    CCDS37484.1
    UniProtKB/Swiss-Prot
    P51944
    Related
    ENSMUSP00000111048.4, ENSMUST00000115390.5
    Conserved Domains (3) summary
    smart00256
    Location:3573
    FBOX; A Receptor for Ubiquitination Targets
    pfam00134
    Location:281406
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:425531
    Cyclin_C; Cyclin, C-terminal domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    24442204..24470383 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006523554.1XP_006523617.1  cyclin-F isoform X1

    Conserved Domains (3) summary
    smart00256
    Location:4886
    FBOX; A Receptor for Ubiquitination Targets
    pfam00134
    Location:296419
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:438544
    Cyclin_C; Cyclin, C-terminal domain
  2. XM_036160284.1XP_036016177.1  cyclin-F isoform X2

    Conserved Domains (1) summary
    cl40454
    Location:179
    CYCLIN_SF; Cyclin box fold superfamily
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