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AFAP1L2 actin filament associated protein 1 like 2 [ Pipistrellus kuhlii (Kuhl's pipistrelle) ]

Gene ID: 118719504, updated on 30-Mar-2024

Summary

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Gene symbol
AFAP1L2
Gene description
actin filament associated protein 1 like 2
Locus tag
mPipKuh1_000412
Gene type
protein coding
RefSeq status
MODEL
Organism
Pipistrellus kuhlii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Pipistrellus
Orthologs
human mouse all
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Genomic context

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See AFAP1L2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current mPipKuh1.p (GCF_014108245.1) Unplaced Scaffold NW_023425460.1 (40409132..40480858, complement)

NW_023425460.1Genomic Context describing neighboring genes Neighboring gene signal peptidase complex subunit 1-like Neighboring gene tudor domain containing 1 Neighboring gene von Willebrand factor A domain containing 2 Neighboring gene actin binding LIM protein 1 Neighboring gene uncharacterized LOC118719509 Neighboring gene uncharacterized LOC123652397 Neighboring gene small nucleolar RNA SNORA62/SNORA6 family

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023425460 Unplaced Scaffold Reference mPipKuh1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH2 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epidermal growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interleukin-8 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of interleukin-6 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
actin filament-associated protein 1-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pipistrellus kuhlii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPipKuh1.p

Genomic

  1. NW_023425460.1 Reference mPipKuh1.p

    Range
    40409132..40480858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045582130.1 → XP_045438086.1  actin filament-associated protein 1-like 2 isoform X13

  2. XM_045582131.1 → XP_045438087.1  actin filament-associated protein 1-like 2 isoform X14

    Conserved Domains (4) summary
    PHA03247
    Location:405 → 508
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:509 → 621
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13307
    Location:218 → 318
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl17171
    Location:69 → 136
    PH-like; Pleckstrin homology-like domain

  3. XM_036439121.2 → XP_036295014.1  actin filament-associated protein 1-like 2 isoform X7

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:484 → 587
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:588 → 693
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:109 → 215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297 → 397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  4. XM_036439120.2 → XP_036295013.1  actin filament-associated protein 1-like 2 isoform X6

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:484 → 587
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:588 → 700
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:109 → 215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297 → 397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  5. XM_036439115.2 → XP_036295008.1  actin filament-associated protein 1-like 2 isoform X3

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    COG1196
    Location:615 → 727
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK14951
    Location:521 → 622
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  6. XM_036439117.2 → XP_036295010.1  actin filament-associated protein 1-like 2 isoform X4

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 721
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  7. XM_036439116.2 → XP_036295009.1  actin filament-associated protein 1-like 2 isoform X2

    UniProtKB/TrEMBL
    A0A7J7VAE8
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  8. XM_036439114.2 → XP_036295007.1  actin filament-associated protein 1-like 2 isoform X1

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  9. XM_036439118.2 → XP_036295011.1  actin filament-associated protein 1-like 2 isoform X5

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  10. XM_036439126.2 → XP_036295019.1  actin filament-associated protein 1-like 2 isoform X1

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  11. XM_036439125.2 → XP_036295018.1  actin filament-associated protein 1-like 2 isoform X11

    UniProtKB/TrEMBL
    A0A7J7VAE8
    Conserved Domains (4) summary
    COG1196
    Location:587 → 692
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    PRK14951
    Location:496 → 594
    PRK14951; DNA polymerase III subunits gamma and tau; Provisional
    cd13306
    Location:109 → 215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297 → 397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  12. XM_036439132.2 → XP_036295025.1  actin filament-associated protein 1-like 2 isoform X15

    UniProtKB/TrEMBL
    A0A7J7VAE8
    Conserved Domains (4) summary
    PHA03247
    Location:484 → 587
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:588 → 693
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:109 → 215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297 → 397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  13. XM_036439124.2 → XP_036295017.1  actin filament-associated protein 1-like 2 isoform X10

    UniProtKB/TrEMBL
    A0A7J7VAE8
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 721
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  14. XM_036439122.2 → XP_036295015.1  actin filament-associated protein 1-like 2 isoform X8

    UniProtKB/TrEMBL
    A0A7J7VAE8
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  15. XM_036439123.2 → XP_036295016.1  actin filament-associated protein 1-like 2 isoform X9

    UniProtKB/TrEMBL
    A0A7J7VA40
    Conserved Domains (4) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    COG1196
    Location:616 → 728
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2

  16. XM_036439127.2 → XP_036295020.1  actin filament-associated protein 1-like 2 isoform X12

    Conserved Domains (3) summary
    PHA03247
    Location:512 → 615
    PHA03247; large tegument protein UL36; Provisional
    cd13306
    Location:137 → 243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325 → 425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
Nucleotide Protein
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