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AFAP1L2 actin filament associated protein 1 like 2 [ Homo sapiens (human) ]

Gene ID: 84632, updated on 27-Nov-2024

Summary

Official Symbol
AFAP1L2provided by HGNC
Official Full Name
actin filament associated protein 1 like 2provided by HGNC
Primary source
HGNC:HGNC:25901
See related
Ensembl:ENSG00000169129 MIM:612420; AllianceGenome:HGNC:25901
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
XB130; KIAA1914; CTB-1144G6.4
Summary
Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in thyroid (RPKM 34.2), spleen (RPKM 23.9) and 15 other tissues See more
Orthologs
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Genomic context

See AFAP1L2 in Genome Data Viewer
Location:
10q25.3
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (114280725..114405175, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (115174841..115299200, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (116054583..116164261, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene tudor domain containing 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:115998924-115999632 Neighboring gene MPRA-validated peak1096 silencer Neighboring gene MPRA-validated peak1097 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116036689-116037189 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116037297-116037798 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:116045355-116045966 Neighboring gene aurora kinase A pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2843 Neighboring gene von Willebrand factor A domain containing 2 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:116079781-116080980 Neighboring gene uncharacterized LOC105378494 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:116088199-116088844 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:116097011-116098210 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116110152-116111044 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2844 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116164296-116164796 Neighboring gene RNA, 7SL, cytoplasmic 384, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116219699-116220200 Neighboring gene actin binding LIM protein 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:116247470-116248669 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr10:116249579-116250078 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4082 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4083 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:116259001-116260200 Neighboring gene Sharpr-MPRA regulatory region 9264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:116278667-116279186 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4085 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4086 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4087 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4088 Neighboring gene Sharpr-MPRA regulatory region 11198 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ14564

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables SH2 domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables SH3 domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein tyrosine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein tyrosine kinase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
actin filament-associated protein 1-like 2
Names
AFAP1-like protein 2
CTB-1144G6.6

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001936.3NP_001001936.1  actin filament-associated protein 1-like 2 isoform 1

    See identical proteins and their annotated locations for NP_001001936.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) lacks an alternate in-frame exon in the 5' coding region, compared to variant 3. It encodes isoform 1, which is shorter than isoform 3.
    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713
    Consensus CDS
    CCDS31286.1
    UniProtKB/Swiss-Prot
    A8K6P7, B3KVQ8, Q2UZW3, Q8N4X5, Q8TB54, Q96PX4, Q96SY5
    UniProtKB/TrEMBL
    B7Z2Q0
    Related
    ENSP00000303042.4, ENST00000304129.9
    Conserved Domains (4) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    pfam00169
    Location:171270
    PH; PH domain
    pfam06583
    Location:516666
    Neogenin_C; Neogenin C-terminus
  2. NM_001287824.2NP_001274753.1  actin filament-associated protein 1-like 2 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).
    Source sequence(s)
    AB067501, AC005383, AK123108, AK291712, AK294969, BC024314, BC035713
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:218324
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:406506
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    pfam00169
    Location:224323
    PH; PH domain
    pfam06583
    Location:569719
    Neogenin_C; Neogenin C-terminus
  3. NM_001351064.2NP_001337993.1  actin filament-associated protein 1-like 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, BC024314, BM918355, DB362446
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:183289
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:371471
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:699765
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26386
    Location:531659
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  4. NM_001351065.2NP_001337994.1  actin filament-associated protein 1-like 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA213501
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:710776
    SMC_N; RecF/RecN/SMC N terminal domain
  5. NM_001351066.2NP_001337995.1  actin filament-associated protein 1-like 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA213501
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:627693
    SMC_N; RecF/RecN/SMC N terminal domain
  6. NM_001351067.2NP_001337996.1  actin filament-associated protein 1-like 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, BM918355, HY263017
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:183289
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:371471
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:699765
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26386
    Location:531659
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  7. NM_001351068.2NP_001337997.1  actin filament-associated protein 1-like 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, BE168197, BM918355
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:183289
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:371471
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:700766
    SMC_N; RecF/RecN/SMC N terminal domain
  8. NM_001351069.2NP_001337998.1  actin filament-associated protein 1-like 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, AL702879, BC024314, BC033212, BC035713, HY263017
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:681747
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26386
    Location:513641
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  9. NM_001351070.2NP_001337999.1  actin filament-associated protein 1-like 2 isoform 10

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, BE168197, BM918355, CN298045
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:109215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:626692
    SMC_N; RecF/RecN/SMC N terminal domain
  10. NM_001351071.2NP_001338000.1  actin filament-associated protein 1-like 2 isoform 11

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA122692, DA213501
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:137243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:654720
    SMC_N; RecF/RecN/SMC N terminal domain
  11. NM_001351072.2NP_001338001.1  actin filament-associated protein 1-like 2 isoform 12

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA122692, DA213501, HY263017
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:137243
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:325425
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:653719
    SMC_N; RecF/RecN/SMC N terminal domain
  12. NM_001351073.2NP_001338002.1  actin filament-associated protein 1-like 2 isoform 13

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, BE168197, BM918355, CN298045, HY263017
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:109215
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:297397
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:625691
    SMC_N; RecF/RecN/SMC N terminal domain
  13. NM_001351074.2NP_001338003.1  actin filament-associated protein 1-like 2 isoform 14

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, AL702879, BC024314, BC033212, BC035713, HY263017
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:681747
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26386
    Location:513641
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  14. NM_001351075.2NP_001338004.1  actin filament-associated protein 1-like 2 isoform 15

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, AL702879, BC024314, BC033212, BC035713, BI053053, BM544228, DA164690, DA785568
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    PRK03918
    Location:599665
    PRK03918; DNA double-strand break repair ATPase Rad50
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
  15. NM_001351076.2NP_001338005.1  actin filament-associated protein 1-like 2 isoform 16

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, AL702879, BC024314, BC033212, BC035713, BI053053, BM544228, DA164690, DA785568
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:599665
    SMC_N; RecF/RecN/SMC N terminal domain
  16. NM_001351077.2NP_001338006.1  actin filament-associated protein 1-like 2 isoform 17

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA213501, DB362446
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    PRK03918
    Location:709775
    PRK03918; DNA double-strand break repair ATPase Rad50
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
  17. NM_001351078.2NP_001338007.1  actin filament-associated protein 1-like 2 isoform 18

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA213501
    Consensus CDS
    CCDS91356.1
    UniProtKB/TrEMBL
    A0A8Q3SIY9, B7Z2Q0
    Related
    ENSP00000512810.1, ENST00000696688.1
    Conserved Domains (3) summary
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:710776
    SMC_N; RecF/RecN/SMC N terminal domain
  18. NM_001351079.2NP_001338008.1  actin filament-associated protein 1-like 2 isoform 19

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, DA213501, DB362446
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:709775
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26386
    Location:541669
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
  19. NM_001351080.2NP_001338009.1  actin filament-associated protein 1-like 2 isoform 20

    Status: VALIDATED

    Source sequence(s)
    AB067501, AC005383, AK123108, BC024314, BC033212, BC035713, BM544228, DA213501
    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (3) summary
    cd13306
    Location:193299
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:381481
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    cl25732
    Location:627693
    SMC_N; RecF/RecN/SMC N terminal domain
  20. NM_032550.4NP_115939.1  actin filament-associated protein 1-like 2 isoform 2

    See identical proteins and their annotated locations for NP_115939.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region, compared to variant 3. It encodes isoform 2, which is shorter than isoform 3.
    Source sequence(s)
    AB067501, AC005383, BC024314
    Consensus CDS
    CCDS31287.1
    UniProtKB/TrEMBL
    B7Z2Q0
    Related
    ENSP00000358276.3, ENST00000369271.7
    Conserved Domains (4) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    pfam00169
    Location:171270
    PH; PH domain
    pfam06583
    Location:516666
    Neogenin_C; Neogenin C-terminus

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    114280725..114405175 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047425858.1XP_047281814.1  actin filament-associated protein 1-like 2 isoform X9

  2. XM_047425857.1XP_047281813.1  actin filament-associated protein 1-like 2 isoform X8

  3. XM_047425856.1XP_047281812.1  actin filament-associated protein 1-like 2 isoform X4

  4. XM_047425854.1XP_047281810.1  actin filament-associated protein 1-like 2 isoform X2

  5. XM_047425855.1XP_047281811.1  actin filament-associated protein 1-like 2 isoform X3

  6. XM_047425853.1XP_047281809.1  actin filament-associated protein 1-like 2 isoform X1

  7. XM_047425873.1XP_047281829.1  actin filament-associated protein 1-like 2 isoform X31

  8. XM_047425865.1XP_047281821.1  actin filament-associated protein 1-like 2 isoform X20

  9. XM_047425864.1XP_047281820.1  actin filament-associated protein 1-like 2 isoform X18

  10. XM_017016804.3XP_016872293.1  actin filament-associated protein 1-like 2 isoform X19

    UniProtKB/TrEMBL
    B7Z2Q0
  11. XM_005270237.6XP_005270294.1  actin filament-associated protein 1-like 2 isoform X17

    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    cd13306
    Location:165271
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:353453
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    pfam00169
    Location:171270
    PH; PH domain
    pfam06583
    Location:516666
    Neogenin_C; Neogenin C-terminus
  12. XM_017016818.2XP_016872307.1  actin filament-associated protein 1-like 2 isoform X27

    UniProtKB/TrEMBL
    B7Z2Q0
  13. XM_017016797.2XP_016872286.1  actin filament-associated protein 1-like 2 isoform X7

    UniProtKB/TrEMBL
    B7Z2Q0
  14. XM_017016798.3XP_016872287.1  actin filament-associated protein 1-like 2 isoform X10

    UniProtKB/TrEMBL
    B7Z2Q0
  15. XM_017016796.2XP_016872285.1  actin filament-associated protein 1-like 2 isoform X6

    UniProtKB/TrEMBL
    B7Z2Q0
  16. XM_047425870.1XP_047281826.1  actin filament-associated protein 1-like 2 isoform X26

  17. XM_047425875.1XP_047281831.1  actin filament-associated protein 1-like 2 isoform X33

  18. XM_017016814.2XP_016872303.1  actin filament-associated protein 1-like 2 isoform X26

    UniProtKB/TrEMBL
    B7Z2Q0
  19. XM_005270233.5XP_005270290.1  actin filament-associated protein 1-like 2 isoform X12

    UniProtKB/TrEMBL
    B7Z2Q0
    Conserved Domains (4) summary
    PRK03918
    Location:700766
    PRK03918; DNA double-strand break repair ATPase Rad50
    cd13306
    Location:183289
    PH1_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 1
    cd13307
    Location:371471
    PH2_AFAP; Actin filament associated protein family Pleckstrin homology (PH) domain, repeat 2
    NF033201
    Location:498633
    Vip_LPXTG_Lm; cell invasion LPXTG protein Vip
  20. XM_017016795.2XP_016872284.1  actin filament-associated protein 1-like 2 isoform X5

    UniProtKB/TrEMBL
    B7Z2Q0
  21. XM_017016832.2XP_016872321.1  actin filament-associated protein 1-like 2 isoform X28

    UniProtKB/TrEMBL
    B7Z2Q0
  22. XM_047425869.1XP_047281825.1  actin filament-associated protein 1-like 2 isoform X24

  23. XM_047425867.1XP_047281823.1  actin filament-associated protein 1-like 2 isoform X22

  24. XM_047425868.1XP_047281824.1  actin filament-associated protein 1-like 2 isoform X23

  25. XM_047425866.1XP_047281822.1  actin filament-associated protein 1-like 2 isoform X21

  26. XM_047425872.1XP_047281828.1  actin filament-associated protein 1-like 2 isoform X30

  27. XM_047425871.1XP_047281827.1  actin filament-associated protein 1-like 2 isoform X29

  28. XM_047425863.1XP_047281819.1  actin filament-associated protein 1-like 2 isoform X16

  29. XM_047425861.1XP_047281817.1  actin filament-associated protein 1-like 2 isoform X14

  30. XM_047425862.1XP_047281818.1  actin filament-associated protein 1-like 2 isoform X15

  31. XM_047425860.1XP_047281816.1  actin filament-associated protein 1-like 2 isoform X13

  32. XM_047425874.1XP_047281830.1  actin filament-associated protein 1-like 2 isoform X32

  33. XM_017016830.2XP_016872319.1  actin filament-associated protein 1-like 2 isoform X34

  34. XM_017016810.2XP_016872299.1  actin filament-associated protein 1-like 2 isoform X25

    UniProtKB/TrEMBL
    B7Z2Q0
  35. XM_047425859.1XP_047281815.1  actin filament-associated protein 1-like 2 isoform X11

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    115174841..115299200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054366963.1XP_054222938.1  actin filament-associated protein 1-like 2 isoform X36

  2. XM_054366976.1XP_054222951.1  actin filament-associated protein 1-like 2 isoform X31

  3. XM_054366969.1XP_054222944.1  actin filament-associated protein 1-like 2 isoform X20

  4. XM_054366967.1XP_054222942.1  actin filament-associated protein 1-like 2 isoform X18

  5. XM_054366968.1XP_054222943.1  actin filament-associated protein 1-like 2 isoform X19

  6. XM_054366966.1XP_054222941.1  actin filament-associated protein 1-like 2 isoform X17

  7. XM_054366974.1XP_054222949.1  actin filament-associated protein 1-like 2 isoform X27

  8. XM_054366962.1XP_054222937.1  actin filament-associated protein 1-like 2 isoform X7

  9. XM_054366964.1XP_054222939.1  actin filament-associated protein 1-like 2 isoform X10

  10. XM_054366961.1XP_054222936.1  actin filament-associated protein 1-like 2 isoform X6

  11. XM_054366973.1XP_054222948.1  actin filament-associated protein 1-like 2 isoform X26

  12. XM_054366978.1XP_054222953.1  actin filament-associated protein 1-like 2 isoform X33

  13. XM_054366972.1XP_054222947.1  actin filament-associated protein 1-like 2 isoform X26

  14. XM_054366965.1XP_054222940.1  actin filament-associated protein 1-like 2 isoform X12

  15. XM_054366960.1XP_054222935.1  actin filament-associated protein 1-like 2 isoform X5

  16. XM_054366959.1XP_054222934.1  actin filament-associated protein 1-like 2 isoform X35

  17. XM_054366975.1XP_054222950.1  actin filament-associated protein 1-like 2 isoform X28

  18. XM_054366970.1XP_054222945.1  actin filament-associated protein 1-like 2 isoform X37

  19. XM_054366977.1XP_054222952.1  actin filament-associated protein 1-like 2 isoform X32

  20. XM_054366979.1XP_054222954.1  actin filament-associated protein 1-like 2 isoform X34

  21. XM_054366971.1XP_054222946.1  actin filament-associated protein 1-like 2 isoform X25