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LRRC56 leucine rich repeat containing 56 [ Homo sapiens (human) ]

Gene ID: 115399, updated on 11-Jun-2021

Summary

Official Symbol
LRRC56provided by HGNC
Official Full Name
leucine rich repeat containing 56provided by HGNC
Primary source
HGNC:HGNC:25430
See related
Ensembl:ENSG00000161328 MIM:618227
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CILD39; DNAAF12
Expression
Broad expression in testis (RPKM 4.5), skin (RPKM 0.8) and 17 other tissues See more
Orthologs
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Genomic context

See LRRC56 in Genome Data Viewer
Location:
11p15.5
Exon count:
18
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (518967..554916)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (537527..554912)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene phosphatidylserine synthase 2 Neighboring gene ribonuclease/angiogenin inhibitor 1 Neighboring gene collagen alpha-2(IV) chain-like Neighboring gene HRas proto-oncogene, GTPase Neighboring gene LMNTD2 antisense RNA 1 Neighboring gene lamin tail domain containing 2 Neighboring gene Ras association domain family member 7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ00101, DKFZp761L1518

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cilium IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
leucine-rich repeat-containing protein 56

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198075.4NP_932341.1  leucine-rich repeat-containing protein 56

    See identical proteins and their annotated locations for NP_932341.1

    Status: VALIDATED

    Source sequence(s)
    AC137894, AP006284, BC035936
    Consensus CDS
    CCDS7700.1
    UniProtKB/Swiss-Prot
    Q8IYG6
    Related
    ENSP00000270115.7, ENST00000270115.8
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    518967..554916
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017017167.1XP_016872656.1  leucine-rich repeat-containing protein 56 isoform X1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  2. XM_011519875.2XP_011518177.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_011518177.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  3. XM_011519877.2XP_011518179.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_011518179.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  4. XM_017017168.1XP_016872657.1  leucine-rich repeat-containing protein 56 isoform X1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  5. XM_006718132.2XP_006718195.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_006718195.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  6. XM_011519876.1XP_011518178.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_011518178.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  7. XM_005252775.2XP_005252832.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_005252832.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  8. XM_005252776.2XP_005252833.1  leucine-rich repeat-containing protein 56 isoform X2

    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat
  9. XM_006718133.2XP_006718196.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_006718196.1

    UniProtKB/Swiss-Prot
    Q8IYG6
    Conserved Domains (4) summary
    cd00116
    Location:54186
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:138175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117170
    LRR_8; Leucine rich repeat

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_187586.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    67168..84552
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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