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DTD2 D-aminoacyl-tRNA deacylase 2 [ Homo sapiens (human) ]

Gene ID: 112487, updated on 11-Jun-2021

Summary

Official Symbol
DTD2provided by HGNC
Official Full Name
D-aminoacyl-tRNA deacylase 2provided by HGNC
Primary source
HGNC:HGNC:20277
See related
Ensembl:ENSG00000129480
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ATD; C14orf126
Expression
Ubiquitous expression in fat (RPKM 6.7), brain (RPKM 4.9) and 25 other tissues See more
Orthologs
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Genomic context

See DTD2 in Genome Data Viewer
Location:
14q12
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (31446036..31457506, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (31915242..31926712, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene asparaginyl-tRNA synthetase 1 pseudogene 1 Neighboring gene HEAT repeat containing 5A Neighboring gene ATP synthase membrane subunit c locus 1 pseudogene 2 Neighboring gene HEATR5A divergent transcript Neighboring gene ribosomal protein L9 pseudogene 4 Neighboring gene G protein-coupled receptor 33

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC9912, FLJ51408

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables Ala-tRNA(Thr) hydrolase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables D-tyrosyl-tRNA(Tyr) deacylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in aminoacyl-tRNA metabolism involved in translational fidelity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in tRNA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
D-aminoacyl-tRNA deacylase 2
Names
D-tyrosyl-tRNA deacylase 2 (putative)
D-tyrosyl-tRNA(Tyr) deacylase 2
L-alanyl-tRNA deacylase
animalia-specifc tRNA deacylase
animalia-specific tRNA deacylase
probable D-tyrosyl-tRNA(Tyr) deacylase 2
putative D-tyrosyl-tRNA deacylase 2
putative D-tyrosyl-tRNA(Tyr) deacylase 2
NP_542395.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_080664.3NP_542395.1  D-aminoacyl-tRNA deacylase 2

    See identical proteins and their annotated locations for NP_542395.1

    Status: VALIDATED

    Source sequence(s)
    AK055367, AL139353, AL163973, BI553940, BU675173
    Consensus CDS
    CCDS9643.1
    UniProtKB/Swiss-Prot
    Q96FN9
    Related
    ENSP00000312224.4, ENST00000310850.9
    Conserved Domains (1) summary
    pfam02580
    Location:11167
    Tyr_Deacylase; D-Tyr-tRNA(Tyr) deacylase

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    31446036..31457506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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