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NR1H3 nuclear receptor subfamily 1 group H member 3 [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105106874, updated on 22-Apr-2024

Summary

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Gene symbol
NR1H3
Gene description
nuclear receptor subfamily 1 group H member 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 12 NC_087447.1 (14358042..14371188, complement)
101 previous assembly CamDro3 (GCF_000803125.2) 10 NC_044520.1 (9868603..9882786, complement)

Chromosome 12 - NC_087447.1Genomic Context describing neighboring genes Neighboring gene myosin binding protein C3 Neighboring gene MAP kinase activating death domain Neighboring gene acid phosphatase 2, lysosomal Neighboring gene damage specific DNA binding protein 2 Neighboring gene transfer RNA proline (anticodon AGG)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
oxysterols receptor LXR-alpha
Names
Oxysterols receptor LXR-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087447.1 Reference mCamDro1.pat

    Range
    14358042..14371188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031459668.2 → XP_031315528.1  oxysterols receptor LXR-alpha isoform X1

    UniProtKB/TrEMBL
    A0A5N4DLJ3
    Conserved Domains (2) summary
    cd06954
    Location:210 → 445
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

  2. XM_031459667.2 → XP_031315527.1  oxysterols receptor LXR-alpha isoform X1

    UniProtKB/TrEMBL
    A0A5N4DLJ3
    Conserved Domains (2) summary
    cd06954
    Location:210 → 445
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

  3. XM_031459666.2 → XP_031315526.1  oxysterols receptor LXR-alpha isoform X1

    UniProtKB/TrEMBL
    A0A5N4DLJ3
    Conserved Domains (2) summary
    cd06954
    Location:210 → 445
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

  4. XM_031459671.2 → XP_031315531.1  oxysterols receptor LXR-alpha isoform X2

    Conserved Domains (2) summary
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers
    cl11397
    Location:210 → 372
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  5. XM_031459669.2 → XP_031315529.1  oxysterols receptor LXR-alpha isoform X1

    UniProtKB/TrEMBL
    A0A5N4DLJ3
    Conserved Domains (2) summary
    cd06954
    Location:210 → 445
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

  6. XM_011000671.3 → XP_010998973.1  oxysterols receptor LXR-alpha isoform X1

    See identical proteins and their annotated locations for XP_010998973.1

    UniProtKB/TrEMBL
    A0A5N4DLJ3
    Conserved Domains (2) summary
    cd06954
    Location:210 → 445
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    cd07160
    Location:78 → 178
    NR_DBD_LXR; DNA-binding domain of Liver X receptors (LXRs) family is composed of two C4-type zinc fingers

  7. XM_011000672.3 → XP_010998974.1  oxysterols receptor LXR-alpha isoform X3

    Conserved Domains (1) summary
    cd06954
    Location:121 → 356
    NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
Nucleotide Protein
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