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RPA1 replication protein A1 [ Ursus maritimus (polar bear) ]

Gene ID: 103667158, updated on 11-Mar-2024

Summary

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Gene symbol
RPA1
Gene description
replication protein A1
See related
Ensembl:ENSUMAG00000009328
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424897.1 (44290264..44354048)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907141.1 (1905091..1968802, complement)

NW_024424897.1Genomic Context describing neighboring genes Neighboring gene serpin family F member 1 Neighboring gene SET and MYND domain containing 4 Neighboring gene pre-B-cell leukemia transcription factor 2-like Neighboring gene reticulon 4 receptor like 1 Neighboring gene diphthamide biosynthesis 1 Neighboring gene OVCA2 serine hydrolase domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication factor A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
replication protein A 70 kDa DNA-binding subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424897.1 Reference ASM1731132v1 Primary Assembly

    Range
    44290264..44354048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008695277.2 → XP_008693499.1  replication protein A 70 kDa DNA-binding subunit isoform X1

    UniProtKB/TrEMBL
    A0A384CG98
    Related
    ENSUMAP00000012546.1
    Conserved Domains (5) summary
    cd04474
    Location:186 → 288
    RPA1_DBD_A; RPA1_DBD_A: A subfamily of OB folds corresponding to the second OB fold, the ssDNA-binding domain (DBD)-A, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    TIGR00617
    Location:2 → 612
    rpa1; replication factor-a protein 1 (rpa1)
    pfam04057
    Location:5 → 104
    Rep-A_N; Replication factor-A protein 1, N-terminal domain
    pfam08646
    Location:461 → 606
    Rep_fac-A_C; Replication factor-A C terminal domain
    pfam16900
    Location:305 → 389
    REPA_OB_2; Replication protein A OB domain

  2. XM_008695278.2 → XP_008693500.1  replication protein A 70 kDa DNA-binding subunit isoform X2

    UniProtKB/TrEMBL
    A0A384CGF9
    Related
    ENSUMAP00000012549.1
    Conserved Domains (1) summary
    TIGR00617
    Location:2 → 581
    rpa1; replication factor-a protein 1 (rpa1)
Nucleotide Protein
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