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Zfr2 zinc finger RNA binding protein 2 [ Mus musculus (house mouse) ]

Gene ID: 103406, updated on 2-Nov-2024

Summary

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Official Symbol
Zfr2provided by MGI
Official Full Name
zinc finger RNA binding protein 2provided by MGI
Primary source
MGI:MGI:2143792
See related
Ensembl:ENSMUSG00000034949 AllianceGenome:MGI:2143792
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1086; 2010013I23Rik; 9130206N08Rik
Summary
Predicted to enable double-stranded RNA binding activity and single-stranded RNA binding activity. Is expressed in cortical plate. Orthologous to human ZFR2 (zinc finger RNA binding protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in cortex adult (RPKM 14.6), frontal lobe adult (RPKM 13.3) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Zfr2 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (81068967..81087957)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (81233133..81252123)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ataxia, cerebellar, Cayman type, opposite strand Neighboring gene nicotinamide riboside kinase 2 Neighboring gene ataxia, cerebellar, Cayman type Neighboring gene megakaryocyte-associated tyrosine kinase Neighboring gene STARR-positive B cell enhancer ABC_E6886 Neighboring gene mitochondrial ribosomal protein L54

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse. Cauchi LM, et al. Dev Biol, 2022 Sep. PMID 35679955
  2. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Feb 28. PMID 12693553
  3. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse.
    Title: Zinc finger RNA binding protein 2 (ZFR2) is not required for male fertility in the mouse.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables double-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
zinc finger RNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034895.3 → NP_001030067.2  zinc finger RNA-binding protein 2

    Status: VALIDATED

    Source sequence(s)
    AC155932, AK033649, AW045600, BB641594, BF449481, BQ042879, CB249573
    Consensus CDS
    CCDS48642.1
    UniProtKB/TrEMBL
    E9Q5M4
    Related
    ENSMUSP00000113913.2, ENSMUST00000117798.8
    Conserved Domains (4) summary
    smart00451
    Location:205 → 232
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:207 → 253
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam09786
    Location:72 → 169
    CytochromB561_N; Cytochrome B561, N terminal
    cl02675
    Location:586 → 837
    DZF; DZF domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    81068967..81087957
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001779403.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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