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IL6 interleukin 6 [ Panthera tigris (tiger) ]

Gene ID: 102968780, updated on 10-Mar-2024

Summary

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Gene symbol
IL6
Gene description
interleukin 6
See related
Ensembl:ENSPTIG00000016661
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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See IL6 in Genome Data Viewer
Location:
chromosome: A2
Exon count:
7
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) A2 NC_056661.1 (113881088..113886613)

Chromosome A2 - NC_056661.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122233983 Neighboring gene glutamate-rich protein 2-like Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene translocase of outer mitochondrial membrane 7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056661.1 Chromosome A2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-6 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T-helper 17 cell lineage commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-6
Names
interleukin 6 (interferon, beta 2)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056661.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    113881088..113886613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007089067.3 → XP_007089129.3  interleukin-6 isoform X1

    UniProtKB/TrEMBL
    A0A8C9K8W4
    Conserved Domains (1) summary
    smart00126
    Location:70 → 223
    IL6; Interleukin-6 homologues

  2. XM_015540660.1 → XP_015396146.1  interleukin-6 isoform X2

    Conserved Domains (1) summary
    cl02473
    Location:1 → 141
    IL6; Interleukin-6/G-CSF/MGF family

  3. XM_015540659.2 → XP_015396145.1  interleukin-6 isoform X2

    Conserved Domains (1) summary
    cl02473
    Location:1 → 141
    IL6; Interleukin-6/G-CSF/MGF family
Nucleotide Protein
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