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ERBB3 erb-b2 receptor tyrosine kinase 3 [ Alligator sinensis (Chinese alligator) ]

Gene ID: 102376821, updated on 11-Apr-2024

Summary

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Gene symbol
ERBB3
Gene description
erb-b2 receptor tyrosine kinase 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
102 current ASM45574v1 (GCF_000455745.1) Unplaced Scaffold NW_005842812.1 (414518..425611)

NW_005842812.1Genomic Context describing neighboring genes Neighboring gene IKAROS family zinc finger 4 Neighboring gene ribosomal protein S26 Neighboring gene proliferation-associated 2G4 Neighboring gene uncharacterized LOC106722874

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005842812 Unplaced Scaffold Reference ASM45574v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuregulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuregulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor tyrosine-protein kinase erbB-3
Names
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Alligator sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM45574v1 Primary Assembly

Genomic

  1. NW_005842812.1 Reference ASM45574v1 Primary Assembly

    Range
    414518..425611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025191369.1 → XP_025047154.1  receptor tyrosine-protein kinase erbB-3

    UniProtKB/TrEMBL
    A0A3Q0FIQ4
    Conserved Domains (5) summary
    cd12095
    Location:593 → 631
    TM_ErbB3; Transmembrane domain of ErbB3, a Protein Tyrosine Kinase
    pfam00757
    Location:128 → 278
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:302 → 419
    Recep_L_domain; Receptor L domain
    pfam14843
    Location:446 → 584
    GF_recep_IV; Growth factor receptor domain IV
    cl21453
    Location:652 → 913
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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