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NLRP12 NLR family pyrin domain containing 12 [ Bos mutus (wild yak) ]

Gene ID: 102266337, updated on 10-Mar-2024

Summary

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Gene symbol
NLRP12
Gene description
NLR family pyrin domain containing 12
Locus tag
M91_03250
See related
Ensembl:ENSBMUG00000013939
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005395682.1 (63485..82558)

NW_005395682.1Genomic Context describing neighboring genes Neighboring gene cationic amino acid transporter 3-like Neighboring gene cationic amino acid transporter 3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005395682.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The yak genome and adaptation to life at high altitude. Qiu Q, et al. Nat Genet, 2012 Jul 1. PMID 22751099

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to cytokine stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NACHT, LRR and PYD domains-containing protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005395682.1 Reference BosGru_v2.0 Primary Assembly

    Range
    63485..82558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005908104.2 → XP_005908166.1  NACHT, LRR and PYD domains-containing protein 12

    UniProtKB/TrEMBL
    L8HSS9
    Related
    ENSBMUP00000018456.1, ENSBMUT00000021327.1
    Conserved Domains (5) summary
    cd00116
    Location:738 → 1028
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:709 → 737
    LRR_RI; leucine-rich repeat [structural motif]
    pfam02758
    Location:12 → 88
    PYRIN; PAAD/DAPIN/Pyrin domain
    pfam05729
    Location:212 → 380
    NACHT; NACHT domain
    pfam14484
    Location:129 → 200
    FISNA; Fish-specific NACHT associated domain
Nucleotide Protein
Heading Accession and Version

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