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dusp10 dual specificity phosphatase 10 [ Maylandia zebra (zebra mbuna) ]

Gene ID: 101482904, updated on 8-Mar-2024

Summary

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Gene symbol
dusp10
Gene description
dual specificity phosphatase 10
See related
Ensembl:ENSMZEG00005001255
Gene type
protein coding
RefSeq status
MODEL
Organism
Maylandia zebra
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Maylandia; Maylandia zebra complex
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG15
Exon count:
4
Annotation release Status Assembly LG Location
104 current M_zebra_UMD2a (GCF_000238955.4) LG15 NC_036794.1 (13597306..13610476, complement)
101 previous assembly MetZeb1.1 (GCF_000238955.1) Unplaced Scaffold NW_004531734.1 (415035..428208, complement)

Linkage Group LG15 - NC_036794.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member F6 Neighboring gene H2.0-like homeo box 1 (Drosophila) Neighboring gene TATA box binding protein (TBP)-associated factor, RNA polymerase I, A Neighboring gene MIA SH3 domain ER export factor 3 Neighboring gene axin interactor, dorsalization associated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of JUN kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Maylandia zebra Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_zebra_UMD2a Primary Assembly

Genomic

  1. NC_036794.1 Reference M_zebra_UMD2a Primary Assembly

    Range
    13597306..13610476 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004550433.3 → XP_004550490.1  dual specificity protein phosphatase 10

    UniProtKB/TrEMBL
    A0A3P9AUY6
    Related
    ENSMZEP00005001530.1, ENSMZET00005001620.1
    Conserved Domains (2) summary
    cd00127
    Location:311 → 449
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:140 → 275
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
Nucleotide Protein
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