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NTRK3 neurotrophic receptor tyrosine kinase 3 [ Saimiri boliviensis (Bolivian squirrel monkey) ]

Gene ID: 101048153, updated on 11-Apr-2024

Summary

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Gene symbol
NTRK3
Gene description
neurotrophic receptor tyrosine kinase 3
See related
EnsemblRapid:ENSSBOG00000029993
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Saimiri boliviensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Saimiriinae; Saimiri
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current BCM_Sbol_2.0 (GCF_016699345.1) Unplaced Scaffold NW_024100936.1 (18807154..19186006)

NW_024100936.1Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S11 Neighboring gene mitochondrial ribosomal protein L46 Neighboring gene U6 spliceosomal RNA Neighboring gene AGBL carboxypeptidase 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024100936 Unplaced Scaffold Reference BCM_Sbol_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nerve growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NT-3 growth factor receptor
Names
neurotrophic tyrosine kinase receptor type 3
NP_001266902.1
XP_010345105.1
XP_010345114.1
XP_010345121.1
XP_039335760.1
XP_039335761.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001279973.1 → NP_001266902.1  NT-3 growth factor receptor precursor

    See identical proteins and their annotated locations for NP_001266902.1

    Status: PROVISIONAL

    Source sequence(s)
    AY665246
    UniProtKB/Swiss-Prot
    Q5IS82
    UniProtKB/TrEMBL
    A0A2K6U9E7
    Related
    ENSSBOP00000028603.2, ENSSBOT00000045483.2
    Conserved Domains (8) summary
    cd04971
    Location:319 → 396
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:211 → 301
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    smart00219
    Location:538 → 810
    TyrKc; Tyrosine kinase, catalytic domain
    smart00410
    Location:218 → 301
    IG_like; Immunoglobulin like
    cd05094
    Location:532 → 818
    PTKc_TrkC; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase C
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

RefSeqs of Annotated Genomes: Saimiri boliviensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCM_Sbol_2.0 Primary Assembly

Genomic

  1. NW_024100936.1 Reference BCM_Sbol_2.0 Primary Assembly

    Range
    18807154..19186006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010346812.2 → XP_010345114.1  NT-3 growth factor receptor isoform X5

    UniProtKB/TrEMBL
    A0A2K6U9E7, A0A2K6U9L5, A0A2K6U9N8
    Related
    ENSSBOP00000028596.1, ENSSBOT00000045476.2
    Conserved Domains (8) summary
    cd04971
    Location:319 → 396
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:211 → 301
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    smart00219
    Location:538 → 824
    TyrKc; Tyrosine kinase, catalytic domain
    smart00410
    Location:218 → 301
    IG_like; Immunoglobulin like
    cd05094
    Location:532 → 832
    PTKc_TrkC; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase C
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  2. XM_010346803.2 → XP_010345105.1  NT-3 growth factor receptor isoform X1

    UniProtKB/TrEMBL
    A0A2K6U9E7, A0A2K6U9K9
    Conserved Domains (8) summary
    cd04971
    Location:319 → 396
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:211 → 301
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    smart00219
    Location:530 → 802
    TyrKc; Tyrosine kinase, catalytic domain
    smart00410
    Location:218 → 301
    IG_like; Immunoglobulin like
    cd05094
    Location:524 → 810
    PTKc_TrkC; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase C
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  3. XM_010346819.2 → XP_010345121.1  NT-3 growth factor receptor isoform X2

    UniProtKB/TrEMBL
    A0A2K6U9J3
    Related
    ENSSBOP00000028545.2, ENSSBOT00000045425.2
    Conserved Domains (7) summary
    cd04971
    Location:319 → 396
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:211 → 301
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    smart00013
    Location:31 → 56
    LRRNT; Leucine rich repeat N-terminal domain
    smart00410
    Location:218 → 301
    IG_like; Immunoglobulin like
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  4. XM_039479827.1 → XP_039335761.1  NT-3 growth factor receptor isoform X4

    UniProtKB/TrEMBL
    A0A2K6U9H4, A0A2K6U9J3
    Conserved Domains (7) summary
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam00047
    Location:214 → 299
    ig; Immunoglobulin domain
    pfam01462
    Location:31 → 51
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd00096
    Location:218 → 221
    Ig; Ig strand A' [structural motif]
    cd04971
    Location:304 → 396
    IgI_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB, and TrkC; member of the I-set of Ig superfamily (IgSF) domains

  5. XM_039479826.1 → XP_039335760.1  NT-3 growth factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A2K6U9J3
    Conserved Domains (7) summary
    sd00031
    Location:105 → 128
    LRR_1; leucine-rich repeat [structural motif]
    pfam00047
    Location:214 → 299
    ig; Immunoglobulin domain
    pfam01462
    Location:31 → 51
    LRRNT; Leucine rich repeat N-terminal domain
    pfam13855
    Location:103 → 160
    LRR_8; Leucine rich repeat
    pfam16920
    Location:163 → 208
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd00096
    Location:218 → 221
    Ig; Ig strand A' [structural motif]
    cd04971
    Location:304 → 396
    IgI_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB, and TrkC; member of the I-set of Ig superfamily (IgSF) domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5IS82.1 GenPept UniProtKB/Swiss-Prot:Q5IS82

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