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Zfp513 zinc finger protein 513 [ Mus musculus (house mouse) ]

Gene ID: 101023, updated on 26-Sep-2022

Summary

Official Symbol
Zfp513provided by MGI
Official Full Name
zinc finger protein 513provided by MGI
Primary source
MGI:MGI:2141255
See related
Ensembl:ENSMUSG00000043059 AllianceGenome:MGI:2141255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf513; D430028M17Rik
Summary
Enables transcription cis-regulatory region binding activity. Predicted to be involved in regulation of transcription, DNA-templated and retina development in camera-type eye. Predicted to be located in nucleus. Is expressed in early conceptus and genitourinary system. Human ortholog(s) of this gene implicated in retinitis pigmentosa 58. Orthologous to human ZNF513 (zinc finger protein 513). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 22.0), adrenal adult (RPKM 21.8) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp513 in Genome Data Viewer
Location:
5; 5 B1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31356325..31360007, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31198981..31202663, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B, subunit 4 delta Neighboring gene sorting nexin 17 Neighboring gene protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform Neighboring gene nuclear receptor binding protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription cis-regulatory region binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retina development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177901.1NP_001171372.1  zinc finger protein 513 isoform 2

    See identical proteins and their annotated locations for NP_001171372.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC114619, BC058976
    Consensus CDS
    CCDS51458.1
    UniProtKB/Swiss-Prot
    Q6PD29
    Related
    ENSMUSP00000031562.9, ENSMUST00000031562.11
    Conserved Domains (3) summary
    COG5048
    Location:412485
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:150170
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:400423
    zf-H2C2_2; Zinc-finger double domain
  2. NM_175311.4NP_780520.3  zinc finger protein 513 isoform 1

    See identical proteins and their annotated locations for NP_780520.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC058976, CJ076079
    Consensus CDS
    CCDS19178.2
    UniProtKB/Swiss-Prot
    Q6PD29, Q8BWH6
    Related
    ENSMUSP00000110238.2, ENSMUST00000114590.8
    Conserved Domains (3) summary
    COG5048
    Location:414487
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:152172
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:402425
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    31356325..31360007 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503657.3XP_006503720.3  zinc finger protein 513 isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:455528
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:193213
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:233258
    zf-H2C2_2; Zinc-finger double domain
  2. XM_030254033.2XP_030109893.1  zinc finger protein 513 isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:352425
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:90110
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:130155
    zf-H2C2_2; Zinc-finger double domain