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Ogdh oxoglutarate dehydrogenase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100764862, updated on 8-Mar-2024

Summary

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Gene symbol
Ogdh
Gene description
oxoglutarate dehydrogenase
Locus tag
I79_011865
See related
Ensembl:ENSCGRG00015000288
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614085.1 (742616..811610)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (98512688..98581410, complement)

NW_003614085.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118239921 Neighboring gene transmembrane p24 trafficking protein 4 Neighboring gene zinc finger MIZ-type containing 2 Neighboring gene peptidylprolyl isomerase A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of oxoglutarate dehydrogenase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
2-oxoglutarate dehydrogenase, mitochondrial
Names
2-oxoglutarate dehydrogenase E1 component, mitochondrial
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
oxoglutarate dehydrogenase (lipoamide)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614085.1 Reference CriGri_1.0 Primary Assembly

    Range
    742616..811610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007645271.4 → XP_007643461.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_007643461.1

    UniProtKB/TrEMBL
    A0A061IQ42, A0A061IQ43
    Conserved Domains (5) summary
    PRK09404
    Location:49 → 1011
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:260 → 523
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:645 → 860
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:47 → 82
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:867 → 1010
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  2. XM_003504758.5 → XP_003504806.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_003504806.1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4
    Conserved Domains (5) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:264 → 527
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:649 → 864
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:47 → 82
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:871 → 1014
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  3. XM_007645269.4 → XP_007643459.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    See identical proteins and their annotated locations for XP_007643459.1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4
    Conserved Domains (5) summary
    PRK09404
    Location:49 → 1015
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
    cd02016
    Location:264 → 527
    TPP_E1_OGDC_like; Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of ...
    pfam02779
    Location:649 → 864
    Transket_pyr; Transketolase, pyrimidine binding domain
    pfam16078
    Location:47 → 82
    2-oxogl_dehyd_N; 2-oxoglutarate dehydrogenase N-terminus
    pfam16870
    Location:871 → 1014
    OxoGdeHyase_C; 2-oxoglutarate dehydrogenase C-terminal

  4. XM_027438218.2 → XP_027294019.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276807.1 Alternate CriGri-PICRH-1.0

    Range
    98512688..98581410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027388170.2 → XP_027243971.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4
    Related
    ENSCGRP00015000496.2, ENSCGRT00015000661.2

  2. XM_027388173.2 → XP_027243974.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A061IQ42, A0A061IQ43
    Related
    ENSCGRP00015000466.1, ENSCGRT00015000627.2

  3. XM_027388171.2 → XP_027243972.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4

  4. XM_027388172.2 → XP_027243973.1  2-oxoglutarate dehydrogenase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A061IMB7, A0A061IPE4
Nucleotide Protein Strain
Heading Accession and Version

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