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RELA RELA proto-oncogene, NF-kB subunit [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100588439, updated on 8-Mar-2024

Summary

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Gene symbol
RELA
Gene description
RELA proto-oncogene, NF-kB subunit
See related
EnsemblRapid:ENSNLEG00000028853
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 4 NC_044384.1 (85295006..85304497, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 4 NC_019819.1 (86100463..86110185, complement)

Chromosome 4 - NC_044384.1Genomic Context describing neighboring genes Neighboring gene pecanex 3 Neighboring gene signal-induced proliferation-associated 1 Neighboring gene lysine acetyltransferase 5 Neighboring gene ribonuclease H2 subunit C Neighboring gene keratin, type II cytoskeletal 8-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to cytokine IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor p65
Names
v-rel reticuloendotheliosis viral oncogene homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044384.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    85295006..85304497 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003274199.4 → XP_003274247.2  transcription factor p65

    UniProtKB/TrEMBL
    A0A2I3GZ54
    Related
    ENSNLEP00000036502.2, ENSNLET00000054119.2
    Conserved Domains (2) summary
    cd07885
    Location:19 → 187
    RHD-n_RelA; N-terminal sub-domain of the Rel homology domain (RHD) of RelA
    cd01177
    Location:194 → 290
    IPT_NFkappaB; IPT domain of the transcription factor NFkappaB and related transcription factors. NFkappaB is considered a central regulator of stress responses, activated by different stressful conditions, including physical stress, oxidative stress, and exposure to ...
Nucleotide Protein
Heading Accession and Version

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