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FZD2 frizzled class receptor 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100452043, updated on 26-Mar-2024

Summary

Gene symbol
FZD2
Gene description
frizzled class receptor 2
Locus tag
CR201_G0023711
See related
Ensembl:ENSPPYG00000008328
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
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Genomic context

Location:
chromosome: 19
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 19 NC_072004.2 (74860166..74864540)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 17 NC_072002.1 (63304832..63307215)

Chromosome 19 - NC_072004.2Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha 2b Neighboring gene G-patch domain containing 8 Neighboring gene uncharacterized LOC129051404 Neighboring gene uncharacterized LOC112129715 Neighboring gene meiosis specific with coiled-coil domain Neighboring gene coiled-coil domain containing 43

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
frizzled-2
Names
frizzled 2, seven transmembrane spanning receptor
frizzled family receptor 2
frizzled homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_072004.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    74860166..74864540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002827431.6XP_002827477.1  frizzled-2

    See identical proteins and their annotated locations for XP_002827477.1

    UniProtKB/TrEMBL
    A0A2J8UYK4, A0A663DHV6, H2NTT7
    Related
    ENSPPYP00000009362.1
    Conserved Domains (2) summary
    cd07464
    Location:35161
    CRD_FZ2; Cysteine-rich Wnt-binding domain (CRD) of the frizzled 2 (Fz2) receptor
    cd15245
    Location:234563
    7tmF_FZD2; class F frizzled subfamily 2, member of 7-transmembrane G protein-coupled receptors