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DDX46 DEAD-box helicase 46 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100340899, updated on 8-Mar-2024

Summary

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Gene symbol
DDX46
Gene description
DEAD-box helicase 46
See related
Ensembl:ENSOCUG00000012206
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 3 NC_067376.1 (17434522..17491465)

Chromosome 3 - NC_067376.1Genomic Context describing neighboring genes Neighboring gene secretion associated Ras related GTPase 1B Neighboring gene SEC24 homolog A, COPII coat complex component Neighboring gene calcium modulating ligand Neighboring gene chromosome 3 C5orf24 homolog Neighboring gene thioredoxin domain containing 15

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067376.1 Chromosome 3 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable ATP-dependent RNA helicase DDX46
Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067376.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    17434522..17491465
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008255024.3 → XP_008253246.1  probable ATP-dependent RNA helicase DDX46 isoform X3

    UniProtKB/TrEMBL
    G1T2U6
    Related
    ENSOCUP00000010511.3
    Conserved Domains (3) summary
    COG0513
    Location:344 → 826
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00268
    Location:378 → 581
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:618 → 714
    Helicase_C; Helicase conserved C-terminal domain

  2. XM_008255025.3 → XP_008253247.1  probable ATP-dependent RNA helicase DDX46 isoform X4

    Conserved Domains (3) summary
    COG0513
    Location:343 → 825
    SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    cd00268
    Location:377 → 580
    DEADc; DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif ...
    pfam00271
    Location:617 → 713
    Helicase_C; Helicase conserved C-terminal domain

  3. XM_051843396.1 → XP_051699356.1  probable ATP-dependent RNA helicase DDX46 isoform X1

  4. XM_051843397.1 → XP_051699357.1  probable ATP-dependent RNA helicase DDX46 isoform X2

Nucleotide Protein
Heading Accession and Version

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