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Adra1a adrenoceptor alpha 1A [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100135474, updated on 27-Apr-2024

Summary

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Gene symbol
Adra1a
Gene description
adrenoceptor alpha 1A
See related
Ensembl:ENSCPOG00000038399
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947507.1 (39245140..39327314, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176418.1 (62754478..62835152, complement)

NW_026947507.1Genomic Context describing neighboring genes Neighboring gene dihydropyrimidinase like 2 Neighboring gene PNMA family member 2 Neighboring gene uncharacterized LOC106025724 Neighboring gene stathmin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning and functional expression of the guinea pig alpha(1a)-adrenoceptor. González-Espinosa C, et al. Eur J Pharmacol, 2001 Aug 31. PMID 11527538
  2. Inverse alpha(1A) and alpha(1D) adrenoceptor mRNA expression during isolation of hepatocytes. González-Espinosa C, et al. Eur J Pharmacol, 1999 Nov 19. PMID 10611446

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha1-adrenergic receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of heart rate by epinephrine-norepinephrine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cardiac muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-1A adrenergic receptor
Names
adrenergic receptor, alpha 1a
alpha-1A adrenoceptor
alpha-1A adrenoreceptor
alpha-1C adrenergic receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172912.2 → NP_001166383.2  alpha-1A adrenergic receptor

    Status: VALIDATED

    Source sequence(s)
    JAVRDI010000024
    UniProtKB/Swiss-Prot
    Q9WU25
    UniProtKB/TrEMBL
    A0A286Y0V4
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947507.1 Reference mCavPor4.1

    Range
    39245140..39327314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023561465.2 → XP_023417233.1  alpha-1A adrenergic receptor isoform X1

    UniProtKB/Swiss-Prot
    Q9WU25
    UniProtKB/TrEMBL
    A0A286Y0V4
    Related
    ENSCPOP00000031190.1
    Conserved Domains (1) summary
    cd15325
    Location:27 → 337
    7tmA_alpha1A_AR; alpha-1 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9WU25.2 GenPept UniProtKB/Swiss-Prot:Q9WU25

Gene LinkOut

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