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NTHL1 nth like DNA glycosylase 1 [ Equus caballus (horse) ]

Gene ID: 100065659, updated on 8-Mar-2024

Summary

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Official Symbol
NTHL1provided by VGNC
Official Full Name
nth like DNA glycosylase 1provided by VGNC
Primary source
VGNC:VGNC:20921
See related
Ensembl:ENSECAG00000012595
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See NTHL1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 13 NC_009156.3 (41966046..41972047)
102 previous assembly EquCab2.0 (GCF_000002305.2) 13 NC_009156.2 (40755306..40761312)

Chromosome 13 - NC_009156.3Genomic Context describing neighboring genes Neighboring gene RAB26, member RAS oncogene family Neighboring gene polycystin 1, transient receptor potential channel interacting Neighboring gene microRNA mir-9141 Neighboring gene TSC complex subunit 2 Neighboring gene NHERF family PDZ scaffold protein 2 Neighboring gene neuropeptide W

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in base-excision repair, AP site formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
endonuclease III-like protein 1
Names
nth endonuclease III-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009156.3 Reference EquCab3.0 Primary Assembly

    Range
    41966046..41972047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001915338.4 → XP_001915373.2  endonuclease III-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0S6Q7, A0A9L0TGP3
    Related
    ENSECAP00000086228.1, ENSECAT00000131418.1
    Conserved Domains (3) summary
    smart00525
    Location:281 → 301
    FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
    smart00478
    Location:130 → 279
    ENDO3c; endonuclease III
    COG0177
    Location:121 → 302
    Nth; Endonuclease III [Replication, recombination and repair]

  2. XM_023616593.1 → XP_023472361.1  endonuclease III-like protein 1 isoform X2

    Conserved Domains (1) summary
    COG0177
    Location:28 → 209
    Nth; Endonuclease III [Replication, recombination and repair]
Nucleotide Protein
Heading Accession and Version

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