U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CTNNB1 catenin beta 1 [ Equus caballus (horse) ]

Gene ID: 100055241, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
CTNNB1provided by VGNC
Official Full Name
catenin beta 1provided by VGNC
Primary source
VGNC:VGNC:16939
See related
Ensembl:ENSECAG00000006949
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 16 NC_009159.3 (46111394..46168598, complement)

Chromosome 16 - NC_009159.3Genomic Context describing neighboring genes Neighboring gene trafficking kinesin protein 1 Neighboring gene unc-51 like kinase 4 Neighboring gene uncharacterized LOC111768370 Neighboring gene uncharacterized LOC111768488 Neighboring gene uncharacterized LOC111768371

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_009159.3 Chromosome 16 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Wnt/β-catenin signaling of cartilage canal and osteochondral junction chondrocytes and full thickness cartilage in early equine osteochondrosis. Kinsley MA, et al. J Orthop Res, 2015 Oct. PMID 25676127
  2. Equine CTNNB1 and PECAM1 nucleotide structure and expression analyses in an experimental model of normal and pathological wound repair. Miragliotta V, et al. BMC Physiol, 2008 Jan 31. PMID 18237399, Free PMC Article
  3. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. significantly increased gene expression in early osteochondrosis osteochondral junction chondrocytes compared to controls
    Title: Wnt/β-catenin signaling of cartilage canal and osteochondral junction chondrocytes and full thickness cartilage in early equine osteochondrosis.
  2. temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
    Title: Equine CTNNB1 and PECAM1 nucleotide structure and expression analyses in an experimental model of normal and pathological wound repair.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-catenin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
catenin beta-1
Names
beta catenin 1
catenin (cadherin-associated protein), beta 1, 88kDa

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001122762.1 → NP_001116234.1  catenin beta-1

    See identical proteins and their annotated locations for NP_001116234.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ267491
    UniProtKB/TrEMBL
    A0A9L0R9K8, B1MV73
    Conserved Domains (4) summary
    smart00185
    Location:350 → 390
    ARM; Armadillo/beta-catenin-like repeats
    COG5064
    Location:142 → 431
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:402 → 427
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:583 → 622
    Arm; Armadillo/beta-catenin-like repeat

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009159.3 Reference EquCab3.0 Primary Assembly

    Range
    46111394..46168598 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023619816.1 → XP_023475584.1  catenin beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0R9K8, B1MV73
    Conserved Domains (4) summary
    smart00185
    Location:350 → 390
    ARM; Armadillo/beta-catenin-like repeats
    COG5064
    Location:142 → 431
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:402 → 427
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:583 → 622
    Arm; Armadillo/beta-catenin-like repeat

  2. XM_023619815.1 → XP_023475583.1  catenin beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0R9K8, B1MV73
    Related
    ENSECAP00000005466.2, ENSECAT00000007477.4
    Conserved Domains (4) summary
    smart00185
    Location:350 → 390
    ARM; Armadillo/beta-catenin-like repeats
    COG5064
    Location:142 → 431
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:402 → 427
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:583 → 622
    Arm; Armadillo/beta-catenin-like repeat

  3. XM_023619814.1 → XP_023475582.1  catenin beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0R9K8, B1MV73
    Related
    ENSECAP00000077725.1, ENSECAT00000085616.1
    Conserved Domains (4) summary
    smart00185
    Location:350 → 390
    ARM; Armadillo/beta-catenin-like repeats
    COG5064
    Location:142 → 431
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:402 → 427
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:583 → 622
    Arm; Armadillo/beta-catenin-like repeat

  4. XM_023619813.1 → XP_023475581.1  catenin beta-1 isoform X1

    UniProtKB/TrEMBL
    A0A9L0R9K8, B1MV73
    Conserved Domains (4) summary
    smart00185
    Location:350 → 390
    ARM; Armadillo/beta-catenin-like repeats
    COG5064
    Location:142 → 431
    SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
    sd00043
    Location:402 → 427
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:583 → 622
    Arm; Armadillo/beta-catenin-like repeat
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials