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PTPRK protein tyrosine phosphatase receptor type K [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100030874, updated on 3-Apr-2024

Summary

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Gene symbol
PTPRK
Gene description
protein tyrosine phosphatase receptor type K
See related
Ensembl:ENSMODG00000017661
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 2 NC_077228.1 (400149700..400884134, complement)
103 previous assembly MonDom5 (GCF_000002295.2) 2 NC_008802.1 (400416322..401139710, complement)

Chromosome 2 - NC_077228.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 C6orf58 homolog Neighboring gene uncharacterized LOC103101622 Neighboring gene thymocyte selection associated Neighboring gene purine nucleoside phosphorylase-like Neighboring gene eukaryotic translation initiation factor 3 subunit C-like Neighboring gene uncharacterized LOC130457441

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase kappa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077228.1 Reference mMonDom1.pri

    Range
    400149700..400884134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007484536.3 → XP_007484598.1  receptor-type tyrosine-protein phosphatase kappa isoform X1

    UniProtKB/TrEMBL
    A0A5F8GQ51, F6YJV4
    Related
    ENSMODP00000022019.4
    Conserved Domains (9) summary
    cd06263
    Location:35 → 191
    MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00194
    Location:898 → 1152
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:924 → 1152
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:503 → 588
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:293 → 371
    fn3; Fibronectin type III domain
    pfam00102
    Location:1212 → 1446
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam13895
    Location:197 → 287
    Ig_2; Immunoglobulin domain

  2. XM_056818748.1 → XP_056674726.1  receptor-type tyrosine-protein phosphatase kappa isoform X2

  3. XM_007484539.3 → XP_007484601.1  receptor-type tyrosine-protein phosphatase kappa isoform X4

    UniProtKB/TrEMBL
    A0A5F8GU39
    Conserved Domains (9) summary
    cd06263
    Location:35 → 191
    MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00194
    Location:885 → 1139
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:911 → 1139
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:503 → 588
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:293 → 371
    fn3; Fibronectin type III domain
    pfam00102
    Location:1199 → 1433
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam13895
    Location:197 → 287
    Ig_2; Immunoglobulin domain

  4. XM_007484538.3 → XP_007484600.1  receptor-type tyrosine-protein phosphatase kappa isoform X3

    UniProtKB/TrEMBL
    A0A5F8GU39
    Conserved Domains (9) summary
    cd06263
    Location:35 → 191
    MAM; Meprin, A5 protein, and protein tyrosine phosphatase Mu (MAM) domain. MAM is an extracellular domain which mediates protein-protein interactions and is found in a diverse set of proteins, many of which are known to function in cell adhesion. Members ...
    smart00137
    Location:31 → 191
    MAM; Domain in meprin, A5, receptor protein tyrosine phosphatase mu (and others)
    smart00194
    Location:886 → 1140
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:201 → 287
    IG_like; Immunoglobulin like
    cd00047
    Location:912 → 1140
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:503 → 588
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:293 → 371
    fn3; Fibronectin type III domain
    pfam00102
    Location:1200 → 1434
    Y_phosphatase; Protein-tyrosine phosphatase
    pfam13895
    Location:197 → 287
    Ig_2; Immunoglobulin domain

  5. XM_056818749.1 → XP_056674727.1  receptor-type tyrosine-protein phosphatase kappa isoform X5

Nucleotide Protein
Heading Accession and Version

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