ClinVar Genomic variation as it relates to human health
GRCh37/hg19 Yq11.21-11.223(chrY:14495040-24070172)x0
Germline
Classification
(1)
Pathogenic
criteria provided, single submitter
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
CDY2A | - | - |
GRCh38 GRCh37 |
1 | 82 | |
DDX3Y | - | - |
GRCh38 GRCh37 |
5 | 75 | |
EIF1AY | - | - |
GRCh38 GRCh37 |
- | 79 | |
FAM197Y10 | - | - | - | GRCh37 | - | 79 |
HSFY1 | - | - |
GRCh38 GRCh37 |
1 | 84 | |
HSFY2 | - | - | - |
GRCh38 GRCh37 |
1 | 88 |
KDM5D | - | - |
GRCh38 GRCh37 |
- | 78 | |
NLGN4Y | - | - |
GRCh38 GRCh37 |
10 | 82 | |
PRORY | - | - | - |
GRCh38 GRCh37 |
- | 79 |
RBMY1A1 | - | - |
GRCh38 GRCh37 |
1 | 85 |
There are 15 more genes affected by this variant. See the full set of genes in Variation Viewer (GRCh37).
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
Pathogenic (1) |
|
Dec 3, 2019 | RCV001090078.1 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Jul 08, 2023