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    DYRK2 dual specificity tyrosine phosphorylation regulated kinase 2 [ Gallus gallus (chicken) ]

    Gene ID: 427864, updated on 5-Mar-2024

    Summary

    Symbol
    DYRK2provided by CGNC
    Full Name
    dual specificity tyrosine phosphorylation regulated kinase 2provided by CGNC
    Primary source
    CGNC:7519
    See related
    Ensembl:ENSGALG00010011926
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
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    Genomic context

    See DYRK2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (35025845..35040503)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (35373265..35387934)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene cullin associated and neddylation dissociated 1 Neighboring gene uncharacterized LOC121109185 Neighboring gene uncharacterized LOC121110228 Neighboring gene basic proline-rich protein-like Neighboring gene uncharacterized LOC121109193 Neighboring gene uncharacterized LOC107052884

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein serine/threonine/tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in peptidyl-threonine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    dual specificity tyrosine-phosphorylation-regulated kinase 2
    Names
    dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
    NP_001026651.1
    XP_015137468.1
    XP_015137476.1
    XP_046764505.1
    XP_046764506.1
    XP_046764507.1
    XP_046764508.1
    XP_046798789.1
    XP_046798798.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031480.2NP_001026651.1  dual specificity tyrosine-phosphorylation-regulated kinase 2

      See identical proteins and their annotated locations for NP_001026651.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000012
      UniProtKB/Swiss-Prot
      Q5ZIU3
      Related
      ENSGALP00010016382.1, ENSGALT00010028541.1
      Conserved Domains (2) summary
      smart00220
      Location:147460
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14224
      Location:81460
      PKc_DYRK2_3; Catalytic domain of the protein kinases, Dual-specificity tYrosine-phosphorylated and -Regulated Kinases 2 and 3

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      35025845..35040503
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046942833.1XP_046798789.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1

    2. XM_015281982.4XP_015137468.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2

      Conserved Domains (2) summary
      smart00220
      Location:218531
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14224
      Location:152531
      PKc_DYRK2_3; Catalytic domain of the protein kinases, Dual-specificity tYrosine-phosphorylated and -Regulated Kinases 2 and 3
    3. XM_015281990.4XP_015137476.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X4

      UniProtKB/Swiss-Prot
      Q5ZIU3
      Related
      ENSGALP00010016384.1, ENSGALT00010028543.1
      Conserved Domains (2) summary
      smart00220
      Location:147460
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14224
      Location:81460
      PKc_DYRK2_3; Catalytic domain of the protein kinases, Dual-specificity tYrosine-phosphorylated and -Regulated Kinases 2 and 3
    4. XM_046942842.1XP_046798798.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YD13
      Related
      ENSGALP00010016375.1, ENSGALT00010028532.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      35373265..35387934
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046908549.1XP_046764505.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1

    2. XM_046908550.1XP_046764506.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X2

    3. XM_046908552.1XP_046764508.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X4

      UniProtKB/Swiss-Prot
      Q5ZIU3
    4. XM_046908551.1XP_046764507.1  dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YD13