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    Genome Biol. 2005;6(1):R6. Epub 2004 Dec 23.

    Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis.

    Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P, Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci P, Hayashizaki Y, Buerstedde JM.

    Source

    Institute of Molecular Radiobiology, GSF, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. randolph.caldwell@gsf.de <randolph.caldwell@gsf.de>

    Abstract

    A large number of cDNA inserts were sequenced from a high-quality library of chicken bursal lymphocyte cDNAs. Comparisons to public gene databases indicate that the cDNA collection represents more than 2,000 new, full-length transcripts. This resource defines the structure and the coding potential of a large fraction of B-cell specific and housekeeping genes whose function can be analyzed by disruption in the chicken DT40 B-cell line.

    PMID:
    15642098
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC549067
    Free PMC Article

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