U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    SHANK2 SH3 and multiple ankyrin repeat domains 2 [ Bos taurus (cattle) ]

    Gene ID: 618649, updated on 6-Jun-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SHANK2provided by VGNC
    Official Full Name
    SH3 and multiple ankyrin repeat domains 2provided by VGNC
    Primary source
    VGNC:VGNC:56279
    See related
    BGD:BT28735; Ensembl:ENSBTAG00000003171
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SHANK2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (47557811..48119364, complement)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344223 Neighboring gene cortactin Neighboring gene uncharacterized LOC104976302 Neighboring gene uncharacterized LOC132344213 Neighboring gene uncharacterized LOC132344215 Neighboring gene actin epsilon 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ionotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables synaptic receptor adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    SH3 and multiple ankyrin repeat domains protein 2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      47557811..48119364 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987497.2 → XP_024843265.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

      Conserved Domains (8) summary
      cd09506
      Location:1770 → 1835
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      cd11983
      Location:528 → 579
      SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
      cd00204
      Location:258 → 383
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd00992
      Location:623 → 716
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      sd00045
      Location:263 → 295
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:168 → 243
      Ank_2; Ankyrin repeats (3 copies)
      pfam16511
      Location:57 → 140
      FERM_f0; N-terminal or F0 domain of Talin-head FERM
      cl26464
      Location:958 → 1474
      Atrophin-1; Atrophin-1 family

    2. XM_015461388.3 → XP_015316874.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X3

      Conserved Domains (10) summary
      cd09506
      Location:1777 → 1842
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      smart00454
      Location:1778 → 1844
      SAM; Sterile alpha motif
      cd11983
      Location:528 → 579
      SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
      COG0666
      Location:169 → 243
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:258 → 383
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd00992
      Location:623 → 716
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12796
      Location:270 → 361
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:231 → 285
      Ank_4; Ankyrin repeats (many copies)
      pfam16511
      Location:57 → 140
      FERM_f0; N-terminal or F0 domain of Talin-head FERM
      sd00045
      Location:263 → 295
      ANK; ANK repeat [structural motif]

    3. XM_015461387.3 → XP_015316873.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

      Conserved Domains (10) summary
      cd09506
      Location:1800 → 1865
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      smart00454
      Location:1801 → 1867
      SAM; Sterile alpha motif
      cd11983
      Location:585 → 636
      SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
      COG0666
      Location:169 → 243
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:258 → 383
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd00992
      Location:680 → 773
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12796
      Location:270 → 361
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:231 → 285
      Ank_4; Ankyrin repeats (many copies)
      pfam16511
      Location:57 → 140
      FERM_f0; N-terminal or F0 domain of Talin-head FERM
      sd00045
      Location:263 → 295
      ANK; ANK repeat [structural motif]

    4. XM_005227382.5 → XP_005227439.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

      See identical proteins and their annotated locations for XP_005227439.1

      Conserved Domains (10) summary
      cd09506
      Location:1827 → 1892
      SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
      smart00454
      Location:1828 → 1894
      SAM; Sterile alpha motif
      cd11983
      Location:585 → 636
      SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
      COG0666
      Location:169 → 243
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00204
      Location:258 → 383
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd00992
      Location:680 → 773
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12796
      Location:270 → 361
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:231 → 285
      Ank_4; Ankyrin repeats (many copies)
      pfam16511
      Location:57 → 140
      FERM_f0; N-terminal or F0 domain of Talin-head FERM
      sd00045
      Location:263 → 295
      ANK; ANK repeat [structural motif]

    5. XM_059883125.1 → XP_059739108.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X5

      UniProtKB/TrEMBL
      A0A3Q1NKF7
      Related
      ENSBTAP00000072812.2, ENSBTAT00000086380.2
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials