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Shank2 SH3 and multiple ankyrin repeat domains 2 [ Mus musculus (house mouse) ]

Gene ID: 210274, updated on 22-Apr-2024

Summary

Official Symbol
Shank2provided by MGI
Official Full Name
SH3 and multiple ankyrin repeat domains 2provided by MGI
Primary source
MGI:MGI:2671987
See related
Ensembl:ENSMUSG00000037541 AllianceGenome:MGI:2671987
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ProSAP1; mKIAA1022
Summary
Enables ionotropic glutamate receptor binding activity. Involved in several processes, including learning or memory; modulation of chemical synaptic transmission; and synapse organization. Located in several cellular components, including neurofilament; photoreceptor inner segment; and photoreceptor outer segment. Colocalizes with postsynaptic membrane. Is expressed in cerebral cortex. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human SHANK2 (SH3 and multiple ankyrin repeat domains 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in cortex adult (RPKM 10.4), frontal lobe adult (RPKM 10.3) and 15 other tissues See more
Orthologs
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Genomic context

Location:
7 F5; 7 88.45 cM
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (143531819..143979780)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (143978077..144426043)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene microRNA 6404 Neighboring gene predicted gene, 34445 Neighboring gene microRNA 3105 Neighboring gene STARR-seq mESC enhancer starr_20539 Neighboring gene STARR-positive B cell enhancer mm9_chr7:151319991-151320291 Neighboring gene STARR-seq mESC enhancer starr_20542 Neighboring gene predicted gene 14372 Neighboring gene predicted gene, 34621 Neighboring gene predicted gene, 34561 Neighboring gene cortactin

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (6)  1 citation
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA1022

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables SH3 domain binding ISO
Inferred from Sequence Orthology
more info
 
enables ionotropic glutamate receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ionotropic glutamate receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables structural constituent of postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
enables synaptic receptor adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in adult behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in adult behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in adult locomotory behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in associative learning ISO
Inferred from Sequence Orthology
more info
 
involved_in exploration behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in learning ISO
Inferred from Sequence Orthology
more info
 
involved_in long-term synaptic depression IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in memory IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of hippo signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell population proliferation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of synaptic transmission, glutamatergic IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of postsynapse organization ISO
Inferred from Sequence Orthology
more info
 
involved_in response to xenobiotic stimulus ISO
Inferred from Sequence Orthology
more info
 
involved_in social behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in social behavior ISO
Inferred from Sequence Orthology
more info
 
involved_in synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vocalization behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vocalization behavior ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in asymmetric synapse ISO
Inferred from Sequence Orthology
more info
 
located_in brush border membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in ciliary membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in dendritic spine IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in dendritic spine IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in growth cone ISO
Inferred from Sequence Orthology
more info
 
is_active_in hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
colocalizes_with neurofilament IDA
Inferred from Direct Assay
more info
PubMed 
located_in neurofilament IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
located_in neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
located_in photoreceptor inner segment IDA
Inferred from Direct Assay
more info
PubMed 
located_in photoreceptor outer segment IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
located_in postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with postsynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
colocalizes_with postsynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in presynaptic active zone ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
SH3 and multiple ankyrin repeat domains protein 2
Names
SH3/ankyrin domain gene 2
cortBP1
cortactin-binding protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081370.3NP_001074839.3  SH3 and multiple ankyrin repeat domains protein 2 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate downstream promoter compared to variant 2 and encodes a shorter isoform (a) with a distinct N-terminus compared to isoform b.
    Source sequence(s)
    AC124520, AC140268
    Consensus CDS
    CCDS40201.1
    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Related
    ENSMUSP00000146440.2, ENSMUST00000146006.3
  2. NM_001113373.3NP_001106844.3  SH3 and multiple ankyrin repeat domains protein 2 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (b).
    Source sequence(s)
    AC124520, AC140268, AC152166
    Consensus CDS
    CCDS85484.1
    UniProtKB/TrEMBL
    A0A6I8MWY3
    Related
    ENSMUSP00000101520.3, ENSMUST00000105900.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    143531819..143979780
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006508521.5XP_006508584.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006508584.1

    Conserved Domains (7) summary
    cd09506
    Location:18451910
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11291538
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  2. XM_006508520.5XP_006508583.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006508583.1

    Conserved Domains (7) summary
    cd09506
    Location:18451910
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11291538
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  3. XM_030242323.2XP_030098183.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X11

    Conserved Domains (7) summary
    cd09506
    Location:17881853
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164406
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:10721481
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:625717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  4. XM_030242322.2XP_030098182.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X11

    Conserved Domains (7) summary
    cd09506
    Location:17881853
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164406
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:10721481
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:625717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  5. XM_017322092.3XP_017177581.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X10

    Conserved Domains (6) summary
    cd09506
    Location:18271892
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  6. XM_017322091.3XP_017177580.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X9

    Conserved Domains (6) summary
    cd09506
    Location:18271892
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  7. XM_006508525.5XP_006508588.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X4

    Conserved Domains (7) summary
    cd09506
    Location:18381903
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11221531
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  8. XM_006508526.5XP_006508589.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X5

    Conserved Domains (7) summary
    cd09506
    Location:18361901
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11201529
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  9. XM_006508529.5XP_006508592.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X8

    Conserved Domains (7) summary
    cd09506
    Location:18291894
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11131522
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  10. XM_006508519.5XP_006508582.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006508582.1

    Conserved Domains (7) summary
    cd09506
    Location:18451910
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11291538
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  11. XM_006508524.5XP_006508587.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X3

    Conserved Domains (7) summary
    cd09506
    Location:18381903
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11221531
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  12. XM_006508523.4XP_006508586.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

    Conserved Domains (7) summary
    cd09506
    Location:18411906
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11251534
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  13. XM_006508527.4XP_006508590.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X6

    Conserved Domains (7) summary
    cd09506
    Location:18341899
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11181527
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  14. XM_006508522.5XP_006508585.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006508585.1

    Conserved Domains (7) summary
    cd09506
    Location:18451910
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11291538
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  15. XM_006508528.5XP_006508591.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X7

    Conserved Domains (7) summary
    cd09506
    Location:18311896
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:586637
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164371
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:11151524
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:682774
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  16. XM_006508530.5XP_006508593.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X11

    Conserved Domains (7) summary
    cd09506
    Location:17881853
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164406
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:10721481
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:625717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  17. XM_006508531.5XP_006508594.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X12

    Conserved Domains (7) summary
    cd09506
    Location:17841849
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164406
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:10681477
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:625717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  18. XM_006508532.5XP_006508595.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X13

    UniProtKB/TrEMBL
    D3Z5K8
    Related
    ENSMUSP00000101522.2, ENSMUST00000105902.8
    Conserved Domains (7) summary
    cd09506
    Location:17741839
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:529580
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03095
    Location:164406
    PHA03095; ankyrin-like protein; Provisional
    PHA03247
    Location:10581467
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:625717
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    sd00045
    Location:230261
    ANK; ANK repeat [structural motif]
    cl28922
    Location:55142
    Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
  19. XM_006508534.5XP_006508597.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X15

    UniProtKB/TrEMBL
    A0A6I8MWY3
    Conserved Domains (4) summary
    cd09506
    Location:14061471
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:147198
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03247
    Location:6901099
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:243335
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  20. XM_006508533.3XP_006508596.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X14

    See identical proteins and their annotated locations for XP_006508596.1

    UniProtKB/Swiss-Prot
    E9QPH7, Q3UTK4, Q5DU07, Q80Z38
    UniProtKB/TrEMBL
    A0A6I8MWY3
    Conserved Domains (4) summary
    cd09506
    Location:14091474
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:150201
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03247
    Location:6931102
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:246338
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  21. XM_030242325.2XP_030098185.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X16

    UniProtKB/TrEMBL
    A0A6I8MWY3
    Conserved Domains (4) summary
    cd09506
    Location:13951460
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    cd11983
    Location:150201
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    PHA03247
    Location:6791088
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:246338
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  22. XM_006508535.4XP_006508598.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X17

    UniProtKB/TrEMBL
    A0A6I8MWY3
    Related
    ENSMUSP00000159313.2, ENSMUST00000239495.2
    Conserved Domains (3) summary
    cd09506
    Location:12181283
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:502911
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:55147
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  23. XM_036152869.1XP_036008762.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X22

    Conserved Domains (2) summary
    cd09506
    Location:914979
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:198607
    PHA03247; large tegument protein UL36; Provisional
  24. XM_030242327.1XP_030098187.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Conserved Domains (2) summary
    cd09506
    Location:10851150
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:369778
    PHA03247; large tegument protein UL36; Provisional
  25. XM_030242326.1XP_030098186.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X18

    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Conserved Domains (3) summary
    cd09506
    Location:11781243
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:462871
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:36128
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
  26. XM_006508536.4XP_006508599.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X19

    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Conserved Domains (2) summary
    cd09506
    Location:10851150
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:369778
    PHA03247; large tegument protein UL36; Provisional
  27. XM_030242328.1XP_030098188.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X20

    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Conserved Domains (2) summary
    cd09506
    Location:9611026
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:245654
    PHA03247; large tegument protein UL36; Provisional
  28. XM_030242329.1XP_030098189.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X21

    UniProtKB/TrEMBL
    A0A1C7ZMY3
    Conserved Domains (2) summary
    cd09506
    Location:9541019
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:238647
    PHA03247; large tegument protein UL36; Provisional
  29. XM_036152871.1XP_036008764.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X22

    Conserved Domains (2) summary
    cd09506
    Location:914979
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:198607
    PHA03247; large tegument protein UL36; Provisional
  30. XM_036152870.1XP_036008763.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X22

    Conserved Domains (2) summary
    cd09506
    Location:914979
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    PHA03247
    Location:198607
    PHA03247; large tegument protein UL36; Provisional

RNA

  1. XR_004934051.1 RNA Sequence

  2. XR_004934050.1 RNA Sequence