adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [Danio rerio (zebrafish)] - Gene

Summary

Gene symbol: adamts5
Gene description: ADAM metallopeptidase with thrombospondin type 1 motif 5
See related: Ensembl:ENSDARG00000100307
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (691738..714626, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (696559..719447, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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General protein information

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Preferred Names: A disintegrin and metalloproteinase with thrombospondin motifs 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001302231.1 → NP_001289160.1 A disintegrin and metalloproteinase with thrombospondin motifs 5 precursor

See identical proteins and their annotated locations for NP_001289160.1

Status: PROVISIONAL

Source sequence(s)

JF778846

UniProtKB/TrEMBL

G3G3J8

Related

ENSDARP00000131997.2, ENSDART00000161072.2

Conserved Domains (6) summary

smart00209
Location:504 → 556

TSP1; Thrombospondin type 1 repeats

cd04273
Location:201 → 407

ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...

pfam01421
Location:201 → 410

Reprolysin; Reprolysin (M12B) family zinc metalloprotease

pfam01562
Location:32 → 132

Pep_M12B_propep; Reprolysin family propeptide

pfam05986
Location:667 → 786

ADAM_spacer1; ADAM-TS Spacer 1

cl15456
Location:436 → 490

ADAM_CR; ADAM cysteine-rich