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rbmx2 RNA binding motif protein X-linked 2 [ Danio rerio (zebrafish) ]

Gene ID: 553240, updated on 12-Sep-2024

Summary

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Official Symbol
rbmx2provided by ZNC
Official Full Name
RNA binding motif protein X-linked 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050626-88
See related
Ensembl:ENSDARG00000044380 AllianceGenome:ZFIN:ZDB-GENE-050626-88
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7141316; zgc:113884
Summary
Predicted to enable RNA binding activity. Acts upstream of or within mRNA splicing, via spliceosome. Predicted to be part of U2 snRNP and precatalytic spliceosome. Is expressed in blastodisc and central nervous system. Orthologous to human RBMX2 (RNA binding motif protein X-linked 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (38639001..38647743)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (38591273..38600037)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119 Neighboring gene seven in absentia homolog 2 (Drosophila)-like Neighboring gene TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RES complex is associated with intron definition and required for zebrafish early embryogenesis. Fernandez JP, et al. PLoS Genet, 2018 Jul. PMID 29969449, Free PMC Article
  2. Rab33a and Rab33ba mediate the outgrowth of forebrain commissural axons in the zebrafish brain. Huang L, et al. Sci Rep, 2019 Feb 12. PMID 30755680, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mRNA splicing, via spliceosome IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
RNA-binding motif protein, X-linked 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025166.1 → NP_001020337.1  RNA-binding motif protein, X-linked 2

    See identical proteins and their annotated locations for NP_001020337.1

    Status: PROVISIONAL

    Source sequence(s)
    BC096985
    UniProtKB/TrEMBL
    Q4QRG7
    Conserved Domains (3) summary
    COG0724
    Location:38 → 110
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12411
    Location:27 → 115
    RRM_ist3_like; RNA recognition motif in ist3 family
    pfam12871
    Location:290 → 381
    PRP38_assoc; Pre-mRNA-splicing factor 38-associated hydrophilic C-term

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    38639001..38647743
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005170268.5 → XP_005170325.1  RNA-binding motif protein, X-linked 2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BHL6, F1RAH8
    Related
    ENSDARP00000113381.1, ENSDART00000143373.3
    Conserved Domains (3) summary
    COG0724
    Location:38 → 110
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12411
    Location:27 → 115
    RRM_ist3_like; RNA recognition motif in ist3 family
    pfam12871
    Location:266 → 346
    PRP38_assoc; Pre-mRNA-splicing factor 38-associated hydrophilic C-term

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395097.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    447066..455789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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