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RBMX2 RNA binding motif protein X-linked 2 [ Homo sapiens (human) ]

Gene ID: 51634, updated on 5-Aug-2022

Summary

Official Symbol
RBMX2provided by HGNC
Official Full Name
RNA binding motif protein X-linked 2provided by HGNC
Primary source
HGNC:HGNC:24282
See related
Ensembl:ENSG00000134597 AllianceGenome:HGNC:24282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Snu17; CGI-79
Summary
Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in endometrium (RPKM 8.3), ovary (RPKM 8.2) and 25 other tissues See more
Orthologs
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Genomic context

See RBMX2 in Genome Data Viewer
Location:
Xq26.1
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (130401987..130413656)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (128721817..128733484)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (129535961..129547630)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 14 Neighboring gene G protein-coupled receptor 119 Neighboring gene fibrous sheath interacting protein 2 like, pseudogene Neighboring gene DENND10 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of U2 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of U2 snRNP IC
Inferred by Curator
more info
PubMed 
part_of U2-type precatalytic spliceosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
part_of precatalytic spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of spliceosomal complex IC
Inferred by Curator
more info
PubMed 

General protein information

Preferred Names
RNA-binding motif protein, X-linked 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_054894.1 RefSeqGene

    Range
    5039..16708
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_016024.4NP_057108.2  RNA-binding motif protein, X-linked 2

    See identical proteins and their annotated locations for NP_057108.2

    Status: VALIDATED

    Source sequence(s)
    AA905143, BC063517, HY112998
    Consensus CDS
    CCDS43993.1
    UniProtKB/Swiss-Prot
    Q9Y388, Q9Y3I8
    Related
    ENSP00000339090.4, ENST00000305536.11
    Conserved Domains (1) summary
    cd12411
    Location:27115
    RRM_ist3_like; RNA recognition motif (RRM) found in ist3 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    130401987..130413656
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    128721817..128733484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)