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USP33 ubiquitin specific peptidase 33 [ Pan troglodytes (chimpanzee) ]

Gene ID: 456965, updated on 17-Aug-2024

Summary

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Official Symbol
USP33provided by VGNC
Official Full Name
ubiquitin specific peptidase 33provided by VGNC
Primary source
VGNC:VGNC:10902
Locus tag
CK820_G0028154
See related
Ensembl:ENSPTRG00000000882
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (153255122..153321008)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (77978283..78044177, complement)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene nuclear speckle splicing regulatory protein 1-like Neighboring gene mitoguardin 1 Neighboring gene actin, cytoplasmic 2-like Neighboring gene zinc finger ZZ-type containing 3 Neighboring gene adenylate kinase 5 Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 33
Names
ubiquitin specific protease 33
XP_003308213.1
XP_009422027.1
XP_009422040.1
XP_024202434.1
XP_054523354.1
XP_063673160.1
XP_513509.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    153255122..153321008
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_513509.8 → XP_513509.3  ubiquitin carboxyl-terminal hydrolase 33 isoform X5

    See identical proteins and their annotated locations for XP_513509.3

    UniProtKB/TrEMBL
    A0A2J8LKJ6, A0A6D2W1E0, H2PZ96, K7D8K2
    Related
    ENSPTRP00000001521.4
    Conserved Domains (4) summary
    smart00695
    Location:809 → 893
    DUSP; Domain in ubiquitin-specific proteases
    pfam00443
    Location:154 → 681
    UCH; Ubiquitin carboxyl-terminal hydrolase
    cl02553
    Location:8 → 254
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    cl12116
    Location:703 → 772
    DUSP; DUSP domain

  2. XM_024346666.3 → XP_024202434.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X4

    UniProtKB/TrEMBL
    K7D8K2
    Conserved Domains (4) summary
    smart00695
    Location:801 → 885
    DUSP; Domain in ubiquitin-specific proteases
    pfam00443
    Location:154 → 673
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:30 → 90
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl12116
    Location:695 → 764
    DUSP; DUSP domain

  3. XM_003308165.5 → XP_003308213.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X1

    See identical proteins and their annotated locations for XP_003308213.1

    UniProtKB/TrEMBL
    A0A2J8LKJ4, A0A6D2XF34, H2R0R2, K7D8K2
    Related
    ENSPTRP00000041112.3
    Conserved Domains (4) summary
    smart00695
    Location:840 → 924
    DUSP; Domain in ubiquitin-specific proteases
    pfam00443
    Location:185 → 712
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:61 → 121
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl12116
    Location:734 → 803
    DUSP; DUSP domain

  4. XM_009423752.5 → XP_009422027.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X2

    See identical proteins and their annotated locations for XP_009422027.1

    UniProtKB/TrEMBL
    K7D8K2
    Conserved Domains (6) summary
    smart00695
    Location:832 → 916
    DUSP; Domain in ubiquitin-specific proteases
    cd02674
    Location:473 → 705
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl02553
    Location:185 → 215
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:184 → 704
    UCH; Ubiquitin carboxyl-terminal hydrolase
    pfam02148
    Location:61 → 121
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl12116
    Location:726 → 795
    DUSP; DUSP domain

  5. XM_063817090.1 → XP_063673160.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X6

    UniProtKB/TrEMBL
    A0A2J8LKJ1

  6. XM_054667379.2 → XP_054523354.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X3

    UniProtKB/TrEMBL
    K7D8K2

  7. XM_009423765.5 → XP_009422040.1  ubiquitin carboxyl-terminal hydrolase 33 isoform X7

    Conserved Domains (5) summary
    smart00695
    Location:645 → 729
    DUSP; Domain in ubiquitin-specific proteases
    cd02674
    Location:278 → 518
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cl02553
    Location:1 → 93
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:1 → 517
    UCH; Ubiquitin carboxyl-terminal hydrolase
    cl12116
    Location:539 → 608
    DUSP; DUSP domain
Nucleotide Protein
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