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ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 [ Phascolarctos cinereus (koala) ]

Gene ID: 110214896, updated on 15-Mar-2024

Summary

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Gene symbol
ADAMTS5
Gene description
ADAM metallopeptidase with thrombospondin type 1 motif 5
See related
Ensembl:ENSPCIG00000014186
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018344013.1 (1767956..1850134, complement)

NW_018344013.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF146-like Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 1 Neighboring gene uncharacterized LOC110214897 Neighboring gene uncharacterized LOC110214828 Neighboring gene N-6 adenine-specific DNA methyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018344013 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018344013.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    1767956..1850134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020996011.1 → XP_020851670.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A6P5L0B5
    Related
    ENSPCIP00000018537.2, ENSPCIT00000022896.2
    Conserved Domains (4) summary
    smart00209
    Location:582 → 634
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:279 → 485
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:98 → 184
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:744 → 864
    ADAM_spacer1; ADAM-TS Spacer 1

  2. XM_020996010.1 → XP_020851669.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A6P5L0B5
    Conserved Domains (4) summary
    smart00209
    Location:582 → 634
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:279 → 485
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:98 → 184
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:744 → 864
    ADAM_spacer1; ADAM-TS Spacer 1

  3. XM_020996009.1 → XP_020851668.1  A disintegrin and metalloproteinase with thrombospondin motifs 5

    UniProtKB/TrEMBL
    A0A6P5L0B5
    Related
    ENSPCIP00000018540.2, ENSPCIT00000022899.2
    Conserved Domains (4) summary
    smart00209
    Location:582 → 634
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:279 → 485
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01562
    Location:98 → 184
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:744 → 864
    ADAM_spacer1; ADAM-TS Spacer 1
Nucleotide Protein
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