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TP53 tumor protein p53 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102402069, updated on 10-Mar-2024

Summary

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Gene symbol
TP53
Gene description
tumor protein p53
See related
EnsemblRapid:ENSBALG00030014431
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Also known as
p53
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 3 NC_059159.1 (35718000..35730534)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 3 NC_058345.1 (35664607..35677152)

Chromosome 3 - NC_059159.1Genomic Context describing neighboring genes Neighboring gene ephrin B3 Neighboring gene WD repeat containing antisense to TP53 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC123332654 Neighboring gene ATPase Na+/K+ transporting subunit beta 2 Neighboring gene sex hormone binding globulin Neighboring gene spermidine/spermine N1-acetyltransferase family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation, characterization and functional analysis of full length p53 cDNA from Bubalus bubalis. Singh M, et al. Gene, 2015 Sep 1. PMID 26003295

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Bubalus p53 appears to be more sensitive to mdm2 mediated degradation compared to human p53.
    Title: Isolation, characterization and functional analysis of full length p53 cDNA from Bubalus bubalis.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein tetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cellular tumor antigen p53

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290844.2 → NP_001277773.2  cellular tumor antigen p53

    See identical proteins and their annotated locations for NP_001277773.2

    Status: PROVISIONAL

    Source sequence(s)
    JF792632
    UniProtKB/TrEMBL
    F6MDM8
    Conserved Domains (3) summary
    cd08367
    Location:101 → 282
    P53; P53 DNA-binding domain
    pfam07710
    Location:312 → 348
    P53_tetramer; P53 tetramerisation motif
    pfam08563
    Location:7 → 30
    P53_TAD; P53 transactivation motif

RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059159.1 Reference NDDB_SH_1 Primary Assembly

    Range
    35718000..35730534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006062871.4 → XP_006062933.1  cellular tumor antigen p53 isoform X1

    See identical proteins and their annotated locations for XP_006062933.1

    UniProtKB/TrEMBL
    F6MDM8
    Related
    ENSBALP00030026631.1, ENSBALT00030040230.1
    Conserved Domains (3) summary
    cd08367
    Location:101 → 282
    P53; P53 DNA-binding domain
    pfam07710
    Location:312 → 348
    P53_tetramer; P53 tetramerisation motif
    pfam08563
    Location:7 → 30
    P53_TAD; P53 transactivation motif

  2. XM_044938378.2 → XP_044794313.1  cellular tumor antigen p53 isoform X1

    UniProtKB/TrEMBL
    F6MDM8
    Related
    ENSBALP00030026617.1, ENSBALT00030040188.1
    Conserved Domains (3) summary
    cd08367
    Location:101 → 282
    P53; P53 DNA-binding domain
    pfam07710
    Location:312 → 348
    P53_tetramer; P53 tetramerisation motif
    pfam08563
    Location:7 → 30
    P53_TAD; P53 transactivation motif
Nucleotide Protein
Heading Accession and Version

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