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    dpr19 defective proboscis extension response 19 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34408, updated on 10-May-2024

    Summary

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    Official Symbol
    dpr19provided by FlyBase
    Official Full Name
    defective proboscis extension response 19provided by FlyBase
    Primary source
    FLYBASE:FBgn0032233
    Locus tag
    Dmel_CG13140
    See related
    AllianceGenome:FB:FBgn0032233
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP09705; CG13140; Dmel\CG13140; Dpr-19; Dpr19
    Summary
    Involved in synapse organization. Predicted to be integral component of plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See dpr19 in Genome Data Viewer
    Location:
    31D11-31D11; 2-41 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10376168..10379905)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10376168..10379905)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene rhomboid-5 Neighboring gene uncharacterized protein Neighboring gene garnysstan Neighboring gene uncharacterized protein Neighboring gene Cyclin-dependent kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel role for the 3'-5' exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth. Towler BP, et al. RNA Biol, 2016 Dec. PMID 27630034, Free PMC Article
    2. Deciphering the DNA code for the function of the Drosophila polydactyl zinc finger protein Suppressor of Hairy-wing. Baxley RM, et al. Nucleic Acids Res, 2017 May 5. PMID 28158673, Free PMC Article
    3. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
    4. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
    5. The insulator protein Suppressor of Hairy-wing is an essential transcriptional repressor in the Drosophila ovary. Soshnev AA, et al. Development, 2013 Sep. PMID 23884443, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sensory perception of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse organization IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in neuron projection membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    defective proboscis extension response 19
    Names
    CG13140-PA
    CG13140-PB
    CG13140-PC
    dpr19-PA
    dpr19-PB
    dpr19-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      10376168..10379905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273407.2 → NP_001260336.1  defective proboscis extension response 19, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260336.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKX8
      Conserved Domains (2) summary
      smart00408
      Location:55 → 125
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:50 → 127
      IG_like; Immunoglobulin like

    2. NM_135548.3 → NP_609392.1  defective proboscis extension response 19, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609392.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKX8
      Related
      FBpp0079594
      Conserved Domains (2) summary
      smart00408
      Location:55 → 125
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:50 → 127
      IG_like; Immunoglobulin like

    3. NM_001273408.2 → NP_001260337.1  defective proboscis extension response 19, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260337.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VKX8
      Conserved Domains (2) summary
      smart00408
      Location:55 → 125
      IGc2; Immunoglobulin C-2 Type
      smart00410
      Location:50 → 127
      IG_like; Immunoglobulin like
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKX8 Q9VKX8

    Gene LinkOut

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