enc3 ectodermal-neural cortex 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: enc3provided by ZNC
Official Full Name: ectodermal-neural cortex 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-5742
See related: Ensembl:ENSDARG00000058322 AllianceGenome:ZFIN:ZDB-GENE-030131-5742
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: enc1; enc1l; id:ibd3303; wu:fi15g12
Summary: Predicted to enable actin binding activity. Acts upstream of or within determination of heart left/right asymmetry and determination of liver left/right asymmetry. Is expressed in several structures, including anterior neural rod; germ ring; mesoderm; nervous system; and tail bud. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (10781957..10795946)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (10752275..10766264)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ENC1-like integrates the retinoic acid/FGF signaling pathways to modulate ciliogenesis of Kupffer's Vesicle during zebrafish embryonic development
Title: ENC1-like integrates the retinoic acid/FGF signaling pathways to modulate ciliogenesis of Kupffer's Vesicle during zebrafish embryonic development.

Submit: New GeneRIF Correction

General gene information

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Markers

D1S3689 (e-PCR)
- UniSTS:474267

fi15g12.x1 (e-PCR)
- UniSTS:204478

fj24h04.y1 (e-PCR)
- UniSTS:198868

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within determination of heart left/right asymmetry	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within determination of liver left/right asymmetry	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: ectodermal-neural cortex 3

Names: ectodermal-neural cortex (with BTB-like domain)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001001402.2 → NP_001001402.2 ectodermal-neural cortex 3

See identical proteins and their annotated locations for NP_001001402.2

Status: VALIDATED

Source sequence(s)

BX908398

UniProtKB/TrEMBL

F6P777, Q789P9, Q7ZT06

Related

ENSDARP00000075626.3, ENSDART00000081183.4

Conserved Domains (6) summary

smart00612
Location:539 → 585

Kelch; Kelch domain

PHA03098
Location:60 → 566

PHA03098; kelch-like protein; Provisional

sd00038
Location:330 → 374

Kelch; KELCH repeat [structural motif]

pfam00651
Location:36 → 140

BTB; BTB/POZ domain

pfam01344
Location:329 → 374

Kelch_1; Kelch motif

pfam07707
Location:149 → 251

BACK; BTB And C-terminal Kelch