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    rabl3 RAB, member of RAS oncogene family-like 3 [ Danio rerio (zebrafish) ]

    Gene ID: 403048, updated on 12-Sep-2024

    Summary

    Official Symbol
    rabl3provided by ZNC
    Official Full Name
    RAB, member of RAS oncogene family-like 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040808-11
    See related
    Ensembl:ENSDARG00000040959 AllianceGenome:ZFIN:ZDB-GENE-040808-11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb40b02; wu:fb40b02; zgc:100876
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including lymphocyte differentiation; regulation of Ras protein signal transduction; and regulation of protein lipidation. Predicted to act upstream of or within proteolysis. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See rabl3 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (32649104..32652419)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (32838372..32841670)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene SATB homeobox 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member B11 Neighboring gene granzyme 3, tandem duplicate 2 Neighboring gene granzyme 3, tandem duplicate 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC100876

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in B cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in T cell differentiation in thymus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in natural killer cell differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of Ras protein signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of protein lipidation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205733.1NP_991296.1  rab-like protein 3

      See identical proteins and their annotated locations for NP_991296.1

      Status: PROVISIONAL

      Source sequence(s)
      AY391440
      UniProtKB/Swiss-Prot
      Q6TNS7
      Related
      ENSDARP00000115081.1, ENSDART00000136136.3
      Conserved Domains (1) summary
      cd04102
      Location:7210
      RabL3; Rab GTPase-like family 3 (Rab-like3)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      32649104..32652419
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223354.1XP_068079455.1  rab-like protein 3 isoform X1