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GEO help: Mouse over screen elements for information. |
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| Status |
Public on May 30, 2012 |
| Title |
Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Illumina Beadchip array analyses of mouse embryonic stem cell gene expression profiles in the presence of or upon knockdown of Aurka. An ES complementation 'rescue' system was employed to measure the effects of knockdown (minus Dox). Aurka was rescued to wildtype levels in the presence of Dox (plus Dox). A control rescue ES cell line, with a Luciferase-targeting shRNA, was also assessed.
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| Overall design |
Total of 12 samples; Aurka_R (+/-Dox) and Control_R (+/-Dox); all performed in triplicates
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| Contributor(s) |
Lee D, Su J, Ang Y, Carvajal-Vergara X, Chang B, Sevilla A, Zhao R, Schaniel C, Mulero-Navarro S, Pereira C, Gingold J, Wang H, Zhao R, Darr H, Williamson A, Niu X, Aguilo F, Flores E, Sher Y, Hung M, Whetton A, Gelb B, Moore K, Snoeck H, Ma'ayan A, Lemischka I |
| Citation(s) |
22862944 |
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| Submission date |
Aug 10, 2010 |
| Last update date |
Jun 14, 2018 |
| Contact name |
Yen-Sin Ang |
| Organization name |
Gladstone Institute, UCSF
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| Street address |
1650 Owens Street
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| City |
san francisco |
| State/province |
CALIFORNIA |
| ZIP/Postal code |
94158 |
| Country |
USA |
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| Platforms (1) |
| GPL6885 |
Illumina MouseRef-8 v2.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA131833 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE23541_RAW.tar |
3.1 Mb |
(http)(custom) |
TAR |
| GSE23541_non_normalized.txt.gz |
3.7 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
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