iqcg IQ motif containing G [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: iqcgprovided by ZNC
Official Full Name: IQ motif containing Gprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050419-109
See related: Ensembl:ENSDARG00000068678 AllianceGenome:ZFIN:ZDB-GENE-050419-109
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-222m18.3
Summary: Predicted to enable calmodulin binding activity. Acts upstream of or within definitive hemopoiesis. Located in motile cilium. Is expressed in blastomere; brain; and pleuroperitoneal region. Orthologous to human IQCG (IQ motif containing G). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (27843840..27897217, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (27865600..27918977, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

results collectively allow us to understand IQCG-mediated calcium signalling in haematopoiesis, and propose a model in which IQCG stores CaM at low cytoplasmic calcium concentrations
Title: Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calmodulin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in cilium organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within definitive hemopoiesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within definitive hemopoiesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in sperm axoneme assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in cilium	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IDA Inferred from Direct Assay more info	PubMed
located_in motile cilium	IEA Inferred from Electronic Annotation more info
is_active_in sperm flagellum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: dynein regulatory complex protein 9; IQ domain-containing protein G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001346240.1 → NP_001333169.1 dynein regulatory complex protein 9

Status: VALIDATED

Source sequence(s)

BX649600, BX908394

UniProtKB/Swiss-Prot

A3KQH2

Related

ENSDARP00000144131.2, ENSDART00000175259.2

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007129.7 Reference GRCz11 Primary Assembly

Range

27843840..27897217 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_002665355.4 → XP_002665401.2 IQ domain-containing protein G isoform X1

UniProtKB/TrEMBL

A0A8M1RMF7

Related

ENSDARP00000120852.1, ENSDART00000142068.2

Conserved Domains (1) summary

smart00015
Location:303 → 322

IQ; Calmodulin-binding motif