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    Esr2 estrogen receptor 2 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100731304, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Esr2
    Gene description
    estrogen receptor 2
    See related
    Ensembl:ENSCPOG00000005703
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947514.1 (37017547..37085711)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176399.1 (9199602..9261942, complement)

    NW_026947514.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 1-like Neighboring gene coiled-coil domain-containing protein 170-like Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene spectrin repeat containing nuclear envelope protein 2 Neighboring gene uncharacterized LOC134474206 Neighboring gene small ribosomal subunit protein eS6-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables estrogen response element binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear estrogen receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables steroid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to estradiol stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cellular response to estrogen stimulus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular estrogen receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    estrogen receptor beta
    Names
    estrogen receptor 2 (beta)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947514.1 Reference mCavPor4.1

      Range
      37017547..37085711
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063241114.1 → XP_063097184.1  estrogen receptor beta isoform X3

    2. XM_023566086.2 → XP_023421854.1  estrogen receptor beta isoform X1

      UniProtKB/TrEMBL
      H0W3W2
      Related
      ENSCPOP00000017661.2
      Conserved Domains (3) summary
      cd06949
      Location:282 → 535
      NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
      cd07171
      Location:163 → 244
      NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
      pfam12497
      Location:35 → 141
      ERbeta_N; Estrogen receptor beta

    3. XM_063241113.1 → XP_063097183.1  estrogen receptor beta isoform X2

    Nucleotide Protein
    Heading Accession and Version

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