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    gtf-2H1 BSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176838, updated on 23-Nov-2023

    Summary

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    Gene symbol
    gtf-2H1
    Gene description
    BSD domain-containing protein
    Primary source
    WormBase:WBGene00019821
    Locus tag
    CELE_R02D3.3
    See related
    AllianceGenome:WB:WBGene00019821
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in nucleic acid metabolic process and phosphorylation of RNA polymerase II C-terminal domain. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIIH core complex and transcription factor TFIIH holo complex. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (225439..231773, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein Neighboring gene Thioredoxin domain-containing protein Neighboring gene Protein asunder Neighboring gene EOG090X08PK

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription mechanisms. Blackwell TK, et al. WormBook, 2006 Sep 5. PMID 18050436, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nucleotide-excision repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIIH core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIIH core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIIH holo complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BSD domain-containing protein
    NP_001368352.1
    • Confirmed by transcript evidence
    NP_499880.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      225439..231773 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067479.6 → NP_499880.3  BSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499880.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44499
      Conserved Domains (3) summary
      smart00751
      Location:118 → 174
      BSD; domain in transcription factors and synapse-associated proteins
      cd13229
      Location:8 → 110
      PH_TFIIH; Transcription Factor II H (TFIIH) Pleckstrin homology (PH) domain
      pfam03909
      Location:199 → 247
      BSD; BSD domain

    2. NM_001379998.1 → NP_001368352.1  BSD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PCA7
    Nucleotide Protein
    Heading Accession and Version

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