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    csk1 cyclin-dependent kinase-activating kinase Csk1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543327, updated on 11-Apr-2024

    Summary

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    Gene symbol
    csk1
    Gene description
    cyclin-dependent kinase-activating kinase Csk1
    Locus tag
    SPAC1D4.06c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (648301..649393, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene putative autophagy associated protein Aut12 Neighboring gene miscRNA Neighboring gene EXS domain-containing protein Neighboring gene chaperonin-containing T-complex beta subunit Cct2 Neighboring gene uncharacterized protein Neighboring gene putative CDP-diacylglycerol--inositol 3-phosphatidyltransferase Pis1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of Cak1p-like cyclin-dependent kinase-activating kinases. Tsakraklides V, et al. J Biol Chem, 2002 Sep 6. PMID 12084729
    2. Genome-wide characterization of the phosphate starvation response in Schizosaccharomyces pombe. Carter-O'Connell I, et al. BMC Genomics, 2012 Dec 12. PMID 23231582, Free PMC Article
    3. A CDK-activating kinase network is required in cell cycle control and transcription in fission yeast. Saiz JE, et al. Curr Biol, 2002 Jul 9. PMID 12121616
    4. Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. Molz L, et al. EMBO J, 1993 Apr. PMID 8467814, Free PMC Article
    5. Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast. Hermand D, et al. EMBO J, 2001 Jan 15. PMID 11226158, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables cyclin-dependent protein kinase activating kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular phosphate ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of G2/M transition of mitotic cell cycle EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of meiotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    involved_in signal transduction IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cyclin-dependent kinase-activating kinase Csk1
    NP_593019.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      648301..649393 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018418.1 → NP_593019.1  cyclin-dependent kinase-activating kinase Csk1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593019.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P36615
      Conserved Domains (2) summary
      smart00220
      Location:12 → 247
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:14 → 269
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version

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