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    Kif24 kinesin family member 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 313170, updated on 11-Apr-2024

    Summary

    Official Symbol
    Kif24provided by RGD
    Official Full Name
    kinesin family member 24provided by RGD
    Primary source
    RGD:1307723
    See related
    Ensembl:ENSRNOG00000012735 AllianceGenome:RGD:1307723
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307723
    Summary
    Predicted to enable identical protein binding activity and microtubule motor activity. Predicted to be involved in cilium assembly and microtubule depolymerization. Predicted to be located in centriole. Predicted to be part of protein-containing complex. Orthologous to human KIF24 (kinesin family member 24). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 31.0), Testes (RPKM 26.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    5q22
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (61357078..61423882, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (56561019..56628040, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (57778730..57845642, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120103061 Neighboring gene ubiquitin-associated protein 1 Neighboring gene nudix hydrolase 2 Neighboring gene myogenesis regulating glycosidase

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule motor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule depolymerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      61357078..61423882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111402.2XP_038967330.1  kinesin-like protein KIF24 isoform X2

      UniProtKB/TrEMBL
      A6IIU7
      Conserved Domains (2) summary
      cd09541
      Location:362
      SAM_KIF24-like; SAM domain of KIF24-like subfamily
      cd01367
      Location:233530
      KISc_KIF2_like; Kinesin motor domain, KIF2-like group
    2. XM_006238113.5XP_006238175.1  kinesin-like protein KIF24 isoform X1

      See identical proteins and their annotated locations for XP_006238175.1

      UniProtKB/TrEMBL
      A6IIU7, A6IIU8, D4A7G8
      Related
      ENSRNOP00000035304.4
      Conserved Domains (3) summary
      cd09541
      Location:362
      SAM_KIF24-like; SAM domain of KIF24-like subfamily
      smart00129
      Location:234557
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01367
      Location:233554
      KISc_KIF2_like; Kinesin motor domain, KIF2-like group
    3. XM_017593713.3XP_017449202.1  kinesin-like protein KIF24 isoform X1

      UniProtKB/TrEMBL
      A6IIU7, A6IIU8, D4A7G8
      Conserved Domains (3) summary
      cd09541
      Location:362
      SAM_KIF24-like; SAM domain of KIF24-like subfamily
      smart00129
      Location:234557
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01367
      Location:233554
      KISc_KIF2_like; Kinesin motor domain, KIF2-like group