LOC542391 knotted 1 [Zea mays] - Gene

Summary

Gene symbol: LOC542391
Gene description: knotted 1
Locus tag: ZEAMMB73_Zm00001d033859
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Zea mays
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade; Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea
Also known as: kn1; KN-1; GRMZM2G017087
Annotation information: Annotation category: suggests misassembly
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
103	current	Zm-B73-REFERENCE-NAM-5.0 (GCF_902167145.1)	1	NC_050096.1 (277841315..277849058, complement)
102.20200423	previous assembly	B73 RefGen_v4 (GCF_000005005.2)	1	NC_024459.2 (276073455..276081198, complement)

Chromosome 1 - NC_050096.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata.
Title: An RNA exosome subunit mediates cell-to-cell trafficking of a homeobox mRNA via plasmodesmata.
Analysis of combinatorial binding with stem cell regulator, KNOTTED1 models for RA1 in promoting determinacy.
Title: Regulatory modules controlling maize inflorescence architecture.
It was shown that knotted1 plays a key role in orchestrating the upper levels of a hierarchical gene regulatory network that impacts plant meristem identity and function.
Title: Unraveling the KNOTTED1 regulatory network in maize meristems.
KN1 trafficking requires chaperonin complex; study shows chaperonins are essential for cell-to-cell trafficking of subset of mobile transcription factors and demonstrates importance of chaperonin-dependent protein trafficking for plant stem cell function
Title: Chaperonins facilitate KNOTTED1 cell-to-cell trafficking and stem cell function.
kn1 normally participates in the establishment of proximal/distal polarity in the incipient leaf.
Title: Distal expression of knotted1 in maize leaves leads to reestablishment of proximal/distal patterning and leaf dissection.
KN1 negatively modulates the accumulation of gibberellin (GA) through the control of ga2ox1.
Title: The maize transcription factor KNOTTED1 directly regulates the gibberellin catabolism gene ga2ox1.
kn1 and td1 function in a pathway to maintain meristem homeostasis but their products may interact with different partners during development.
Title: The interaction of knotted1 and thick tassel dwarf1 in vegetative and reproductive meristems of maize.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: homeotic protein knotted-1

Names: H2; H3; PCO065671; SC19; gsy19(kn1); homeobox protein OSH1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001279733.2 → NP_001266662.2 homeotic protein knotted-1

Status: VALIDATED

Source sequence(s)

DW883016, EU961952

UniProtKB/Swiss-Prot

P24345

UniProtKB/TrEMBL

B4FAU3, B6TUD9, Q53ZF1

Conserved Domains (4) summary

pfam03789
Location:242 → 263

ELK; ELK domain

pfam03790
Location:103 → 142

KNOX1; KNOX1 domain

pfam03791
Location:158 → 203

KNOX2; KNOX2 domain

pfam05920
Location:282 → 321

Homeobox_KN; Homeobox KN domain

RefSeqs of Annotated Genomes: Zea mays Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Zm-B73-REFERENCE-NAM-5.0 Primary Assembly

Genomic

NC_050096.1 Reference Zm-B73-REFERENCE-NAM-5.0 Primary Assembly

Range

277841315..277849058 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001111966.2: Suppressed sequence

Description

NM_001111966.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.